Preoperative i.v. Iron Substitution in Patients With Colon Carcinoma and Iron-deficiency Anemia
Who is this study for? Adult patients with Colon Cancer
What treatments are being studied? Ferric Carboxymaltose
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
About 70% of colon cancer patients are anemic. Preoperative anemia in patients with colorectal cancer is associated with both impaired disease-free survival and overall survival. The purpose of this study is to compare the effects of preoperative iv iron substitution on postoperative recovery in preoperatively anemic (male Hb \<130, female Hb \<120) and iron deficient colon cancer patients in a prospective setup. As a primary outcome, the effect of iv-iron substitution on postoperative complications is investigated.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:
• Age\> 18 years
• Dg: Colon ca
• The planned measure: the colon resection
• Men: Hb \<130, women: Hb \<120 and iron deficiency (elevated TfR, low TrFesat or low ferritin)
Locations
Other Locations
Finland
Jorvi Hospital
RECRUITING
Espoo
Contact Information
Primary
Suvi K Rasilainen, Md, PhD
suvi.rasilainen@hus.fi
+35894711
Time Frame
Start Date: 2020-10-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 514
Treatments
Experimental: Iron arm
Half of patients get i.v. iron preoperatively
No_intervention: non-iron arm
Half of patients are treated without i.v. iron substitution
Related Therapeutic Areas
Sponsors
Leads: Helsinki University Central Hospital