Interest of Sublingual Videomicroscopy for the Prediction of Bleeding in Von Willebrand Disease and Other Constitutional Haemorrhagic Diseases
Status: Recruiting
Location: See location...
Intervention Type: Device, Biological
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
In Willebrand disease, there is currently no test available to identify non-invasively patients with a high risk of bleeding from angiodysplasias The study propose to use a sublingual capillary bed analysis by video-microscopy, a sensitive, reproducible and non-invasive technique, to assess whether sublingual capillary density is predictive of hemorrhagic risk for patients with von Willebrand disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Adult patient with a significant form of von Willebrand disease (according to the inclusion criteria of the Willebrand Disease French Reference Center), a Glanzmann Thrombasthenia, a moderate to severe Haemophilia A or a woman carrying the hemophilia gene
• Social insured patient
Locations
Other Locations
France
CHU de Lille
RECRUITING
Lille
Contact Information
Primary
Antoine Rauch, MD,PhD
antoine.rauch@chru-lille.fr
3 20445962 (poste 29673)
Time Frame
Start Date: 2023-05-24
Estimated Completion Date: 2028-05-24
Participants
Target number of participants: 400
Treatments
Experimental: Patients with haemorrhagic disease
Patients with von Willebrand disease or Patients with Glanzmann Thrombasthenia
Other: Control group
Patients with moderate or severe hemophilia A or women carrying the hemophilia gene
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Lille