Faecal Analyses in Spondyloarthritis Therapy: A Prospective Observational Study of the Intestinal Microbiome in Patients With Spondyloarthropathy Receiving TNF-inhibition.

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY

This study evaluates the intestinal microbiome and disease activity in patients with spondyloarthropathies receiving immunosuppressive therapy. Patients will be analysed at two time points in reference to two predefined primary endpoints: * Changes in intestinal microbiome * Response to therapy The investigators want to evaluate if successful treatment of spondylarthropathy coincide with specific changes in the gut flora.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Fulfilling the Assessment of SpondyloArthritis International Society classification criteria for spondyloarthropathy.

• About to commence treatment with TNF-inhibition

Locations
Other Locations
Sweden
Reumatologi SUS Lund, Region Skåne
RECRUITING
Lund
Contact Information
Primary
Kristofer Andréasson, MD PhD
kristofer.andreasson@med.lu.se
+4646172153
Backup
Johan Karlsson Wallman, MD PhD
johan.81.karlsson@gmail.com
+4646172140
Time Frame
Start Date: 2019-01-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 50
Treatments
Responder
Patient responding to TNF-inhibition
non-Responder
Patient not responding to TNF-inhibition
Related Therapeutic Areas
Sponsors
Leads: Region Skane

This content was sourced from clinicaltrials.gov