Learn About Ankylosing Vertebral Hyperostosis with Tylosis

What is the definition of Ankylosing Vertebral Hyperostosis with Tylosis?
A rare dysostosis with predominant vertebral involvement characterized by paraspinal ligament ossification (most pronounced in the lower thoracic region), osteophytosis, marginal sacroiliac joint sclerosis, and punctate hyperkeratosis on the soles and palms. Patients may be asymptomatic or present mild to moderate back pain. There have been no further descriptions in the literature since 1969.
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What are the alternative names for Ankylosing Vertebral Hyperostosis with Tylosis?
  • Ankylosing vertebral hyperostosis with tylosis
  • Familial ankylosing vertebral hyperostosis with tylosis
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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

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