Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder- A Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies? Primary Outcomes: 1. To observe the impacts and outcomes of cerebellar transcranial direct current stimulation (tDCS) on social behaviors measured by Cyberball and Trust Game. 2. To observe the neuropsychological impacts of cerebellar tDCS through fMRI imaging as well as looking at the Region of Interest (ROI) of changes in the Default Mode Network and Cerebellum circuits and their activation levels in those networks. Secondary Outcomes: 1.To observe the impacts and outcome of cerebellar transcranial direct current stimulation (tDCS) measuring the differences between anodal and cathodal stimulation. To observe potential increases in responses to social stimuli, decreases in eating disorder/depressive symptomology via cathodal stimulation. To also observe potential little to no changes in social stimuli and eating disorder/depressive symptomology via anodal stimulation.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 15
Maximum Age: 30
Healthy Volunteers: f
View:

• Diagnosis of Anorexia Nervosa (AN)

• Female participants

• Age 15-30 years old inclusive at time of enrollment

• Ability of parent or legal guardian to provide informed consent if participant is under 18 years old.

• Ability of patients ages 15-17 to give assent to the study.

• Completion of the signed HIPAA authorization form by a parent or legal guardian or by participants (18 years of age).

Locations
United States
Texas
UT Southwestern Multispecialty Psychiatry Clinic
RECRUITING
Dallas
Contact Information
Primary
Haley Walker
haley.walker@utsouthwestern.edu
214-648-4617
Backup
Ava Ryan
Ava.ryan@utsouthwestern.edu
214-648-4617
Time Frame
Start Date: 2024-04-24
Estimated Completion Date: 2026-01-02
Participants
Target number of participants: 15
Treatments
Experimental: anodal tDCS, then cathodal tDCS
Participants receive 1, 20-minute anodal tDCS stimulation. After a washout period of 2-3 weeks, then receive 1, 20-minute cathodal tDCS stimulation.
Experimental: cathodal tDCS, then andoal tDCS
Participants receive 1, 20-minute cathodal tDCS stimulation. After a washout period of 2-3 weeks, then receive 1, 20-minute anodal tDCS stimulation.
Related Therapeutic Areas
Sponsors
Leads: University of Texas Southwestern Medical Center

This content was sourced from clinicaltrials.gov

Similar Clinical Trials