Evaluation of the Sphingolipidomic Profile in Women Suffering From Anorexia Nervosa: Relationship With Clinical-endocrine and Psychiatric Parameters

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

: The objective of this research project will be to determine the sphingolipidomic profile in a group of women (\> 18 years) affected by Anorexia Nervosa (AN), phenotypically characterized (restricting \[AN-R\] vs binge-eating purging \[AN-BP\]). Specific questionnaires will be administered for the definition of the severity of the eating disorder and depressive state (suicidality), to which will be added the evaluation of gonadal function (i.e., plasma levels of estradiol/progesterone and use of oral contraceptives). Based on the specific lipidomic profile, which the present research project hopes to characterize, it will be possible to appropriately modify the diet of rehabilitation programs and, in the future, improve the effectiveness of the treatment itself, especially in the long term.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• Female sex

• Age: 18 years or older

• Diagnosis of Anorexia Nervosa in the acute phase

• Hospitalized at the Division of Eating and Nutrition Disorders (END), San Giuseppe Hospital, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy

• Female sex

• Age: 18 years or older

• BMI between 18.5 and 24.9 kg/m2

Locations
Other Locations
Italy
Istituto Auxologico Italiano IRCCS, Site Piancavallo
RECRUITING
Oggebbio
Contact Information
Primary
Alessandro Sartorio, MD
sartorio@auxologico.it
+390261911
Backup
Luca Grappiolo, Dr.
luca.grappiolo@auxologico.it
+390261911
Time Frame
Start Date: 2024-06-19
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 60
Treatments
Anorexia Nervosa
Adult female Anorexia Nervosa patients, hospitalized at the Division of Eating and Nutrition Disorders (END), Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
Normal weight
Adult normal-weight women with a Body Mass Index between 18.5 and 24.9 kg/m2, recruited from research and hospital staff
Related Therapeutic Areas
Sponsors
Leads: Istituto Auxologico Italiano

This content was sourced from clinicaltrials.gov