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Condition

Aortic Valve Stenosis

Condition 101

What is the definition of Aortic Valve Stenosis?

Aortic valve stenosis (AVS) is a condition characterized by narrowing of the heart's aortic valve opening. This narrowing prevents the valve from opening fully, which obstructs blood flow from the heart into the aorta, and onward to the rest of the body. AVS can range from mild to severe. Sign ...

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What are the alternative names for Aortic Valve Stenosis?

  • Aortic stenosis
  • Valvular aortic stenosis

What are the causes for Aortic Valve Stenosis?

Aortic valve stenosis can be congenital (present at birth) or can develop later in life. When the condition is congenital, it is typically due to abnormal development of the aortic valve - either it forms abnormally narrow, or it is made up of one flap or leaflet (called a unicuspid valve, which is very rare) or two leaflets (bicuspid valve) instead of the usual three. Having a bicuspid valve can run in families. A bicuspid valve may not cause any problems until adulthood, when the valve begins to narrow or leak. In most cases, the exact underlying cause of congenital aortic valve stenosis is unknown. Aortic valve stenosis can also be caused by the buildup of calcium deposits on the heart valve with increasing age. This cause is most common in people older than 65. Rheumatic fever can also cause the condition because it may result in scar tissue forming on the valve, causing the leaflets to stiffen and fuse. Rheumatic fever can also cause a rough surface on the valve, which can lead to accumulation of calcium deposits later in life.

Latest Research

Latest Advance
Study
  • Condition: Symptomatic Aortic Stenosis During COVID-19 Pandemic
  • Journal: CJC open
  • Treatment Used: Transcatheter Aortic Valve Replacement (TAVR)
  • Number of Patients: 0
  • Published —
This article discusses the possibility of ambulatory transcatheter aortic valve replacement (TAVR) for patients with symptomatic aortic stenosis (occlusion) during the COVID-19 pandemic.
Latest Advance
Study
  • Condition: Aortic Stenosis
  • Journal: Circulation. Cardiovascular interventions
  • Treatment Used: Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement
  • Number of Patients: 8107
  • Published —
In this study, researchers compared the effectiveness of transcatheter aortic valve replacement versus surgical aortic valve replacement for the treatment of aortic stenosis in persons with end-stage renal disease.
Latest Advance
Study
  • Condition: Post-Transcatheter Aortic Valve Implantation (TAVI) with a Balloon-Expandable Valve
  • Journal: Circulation. Cardiovascular interventions
  • Treatment Used: Coronary Access (CA) and Percutaneous Coronary Intervention
  • Number of Patients: 1936
  • Published —
This study evaluated patients with the balloon-expandable SAPIEN 3 transcatheter heart valve who underwent coronary access (CA) with or without percutaneous coronary intervention after transcatheter aortic valve implantation (TAVI).
Latest Advance
Study
  • Condition: Fetal Aortic Stenosis
  • Journal: Journal of cardiothoracic surgery
  • Treatment Used: Fetal Aortic Valvuloplasty
  • Number of Patients: 5
  • Published —
This study tested the safety and efficacy of using fetal aortic valvuloplasty to treat patients with fetal aortic stenosis.

Clinical Trials

Clinical Trial
Device
  • Status: Recruiting
  • Study Type: Device
  • Participants: 100
  • Start Date: July 1, 2020
SMART TAVR: SMART Watch Facilitated Early Discharge in Patients Undergoing Transcatheter Aortic Valve Replacement
Clinical Trial
Diagnostic Test
  • Status: Recruiting
  • Study Type: Diagnostic Test
  • Participants: 200
  • Start Date: July 2020
Evaluation of Conduction Disease After Trans-catheter Aortic Valve Replacement
Clinical Trial
Device
  • Status: Recruiting
  • Study Type: Device
  • Participants: 80
  • Start Date: July 1, 2020
TAVI in Intermediate Risk Septuagenarians With Risk Factors Not Captured by the Traditional Surgical Risk Scores