Learn About Aortic Valve Stenosis

What is the definition of Aortic Valve Stenosis?
Aortic valve stenosis (AVS) is a condition characterized by narrowing of the heart's aortic valve opening. This narrowing prevents the valve from opening fully, which obstructs blood flow from the heart into the aorta, and onward to the rest of the body. AVS can range from mild to severe. Signs and symptoms typically develop when the narrowing of the opening is severe and may include chest pain (angina) or tightness; shortness of breath or fatigue (especially during exertion); feeling faint or fainting; heart palpitations; and heart murmur. Individuals with less severe congenital AVS (present at birth) may not develop symptoms until adulthood. Individuals with severe cases may faint without warning. AVS can have several causes including abnormal development before birth (such as having 1 or 2 valve leaflets instead of 3); calcium build-up on the valve in adulthood; and rheumatic fever.
Save information for later
Sign Up
What are the alternative names for Aortic Valve Stenosis?
  • Aortic valve stenosis
  • Aortic stenosis
  • Valvular aortic stenosis
Who are the top Aortic Valve Stenosis Local Doctors?
Learn about our expert tiers
Learn more
What are the latest Aortic Valve Stenosis Clinical Trials?
NHLBI Structural Heart and Valve Network Prospective Registry

Background: Treatments for structural heart and valve disease are quickly changing. But treatment could be improved. Researchers want to gather data from people with this disease. They want to find problems and seek new ways to make treatments better.

Match to trials
Find the right clinical trials for you in under a minute
Get started
ATTR Amyloidosis in Elderly Patients With Aortic Stenosis

Summary: Severe aortic stenosis is defined with a mean transvalvular pressure gradient (MTPG) > 40mmHg and a calculated aortic valve area of < 1cm2. However, a considerable proportion of patients do have a MTPG < 40mmHg due to a reduced stroke volume (stroke volume indexed to body surface area ≤ 35ml/m2) despite a normal left ventricular ejection fraction (LVEF > 50%). This entity is termed paradoxical low...

Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Aortic Valve Stenosis?
Transcatheter and surgical aortic valve replacement in patients with left ventricular dysfunction.
TAVI With or Without Predilation: Trends From a Large, Propensity-Score Weighted German Aortic Valve Registry (GARY) Population.
Tired of the same old research?
Check Latest Advances
Diabetes mellitus in transfemoral transcatheter aortic valve implantation: a propensity matched analysis.