Apolipoprotein C2 DeficiencySymptoms, Doctors, Treatments, Advances & More
Apolipoprotein C2 Deficiency Overview
Learn About Apolipoprotein C2 Deficiency
Condition 101 content is not available at this time, but we are continually updating the site. Please check back.
However, there may be experts who have treated this or similar conditions in our Find a Doctor section and research may be available in our Latest Advances section.
Office
Joseph Witztum is an Endocrinologist practicing medicine in La Jolla, California. Dr. Witztum is rated as an Elite provider by MediFind in the treatment of Apolipoprotein C2 Deficiency. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Apolipoprotein C2 Deficiency, Familial Lipoprotein Lipase Deficiency, Familial Hypertriglyceridemia, and Antigen-Peptide-Transporter 2 Deficiency.
Baylor Medicine Atherosclerosis
Christie Ballantyne is a Cardiologist practicing medicine in Houston, Texas. He has been practicing medicine for over 44 years. Dr. Ballantyne is rated as an Elite provider by MediFind in the treatment of Apolipoprotein C2 Deficiency. He is also highly rated in 22 other conditions, according to our data. His clinical expertise encompasses Familial Hypertriglyceridemia, High Cholesterol, Atherosclerosis, Coronary Artery Bypass Graft (CABG), and Heart Bypass Surgery.
Daniel Gaudet practices practicing medicine in Kelowna, Canada. Mr. Gaudet is rated as an Elite expert by MediFind in the treatment of Apolipoprotein C2 Deficiency. He is also highly rated in 19 other conditions, according to our data. His clinical expertise encompasses High Cholesterol, Familial Lipoprotein Lipase Deficiency, Apolipoprotein C2 Deficiency, and Familial Hypertriglyceridemia.
Summary: This is an open-label, single-arm, dose-escalation Phase I clinical trial to evaluate the safety, tolerability, pharmacodynamics (PD), and pharmacokinetics (PK) of CS-121, an in vivo base editing therapy delivered by lipid nanoparticles targeting APOC3, in adult participants (18-55 years) with familial chylomicronemia syndrome (FCS).
Summary: Lipoprotein lipase (LPL) is an enzyme that plays an important role in removing triglycerides (TG) (molecules that transport dietary fat) from the blood. Patients with LPL deficiency (LPLD) display during their whole life very high plasma TG levels often associated with episodes of postprandial abdominal pain, malaise, blurred vision, dizziness (hyperchylomicronemia syndrome) that may lead to recur...