Interventional Cross-over Study to Evaluate the Efficacy on Motor and Cognitive Performance of Transcranial Alternating Current Stimulation (tACS) in Patients With Neurodegenerative Ataxia
Status: Completed
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of the study is to evaluate the effects on motor and cognitive performance of transcranial alternating current stimulation (tACS) compared to transcranial direct current stimulation (tDCS) and placebo stimulation (sham) in patients with neurodegenerative ataxia to identify a possible rehabilitation protocol.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients with a cerebellar syndrome and quantifiable cerebellar atrophy
Locations
Other Locations
Italy
ASST Spedali Civili di Brescia
Brescia
Time Frame
Start Date: 2021-01-28
Completion Date: 2022-12-10
Participants
Target number of participants: 26
Treatments
Active_comparator: Transcranial direct current stimulation (tDCS)
Single session of anodal tDCS at 2 mA over the cerebellar hemispheres
Active_comparator: Transcranial alternate current stimulation (tDCS)
Single session of gamma tACS (50 Hz) at 3 mA over the cerebellar hemispheres
Sham_comparator: Placebo stimulation (sham)
Single session of sham tDCS over the cerebellar hemispheres
Related Therapeutic Areas
Sponsors
Leads: Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia