Condition 101 About Drug Induced Dyskinesia

What is the definition of Drug Induced Dyskinesia?

Drug induced dyskinesia is an involuntary movement disorder. Signs and symptoms include repetitive and irregular motions of the mouth, face, limbs and/or trunk. Treatment with antipsychotic drugs and levodopa (commonly used to treat Parkinson disease) are well recognized causes of drug-induced dyskinesia. Dyskinesia develops in around 40% of people with Parkinson's disease who have been on levodopa treatment for four to six years. Tardive dyskinesia is a severe form of drug-induced dyskinesia due to antipsychotic treatments. Tardive dyskinesia develops in 5% of people per year of treatment.

What are the alternative names for Drug Induced Dyskinesia?

  • Dyskinesia, drug induced

What are the causes for Drug Induced Dyskinesia?

The following medications have caused drug-induced dyskinesia in some individuals:

  • Levodopa
  • Chlorpromazine
  • Fluphenazine
  • Haloperidol
  • Trifluoperazine
  • Flunarizine (Sibelium)
  • Metoclopramide
  • Prochlorperazine

Latest Advances On Drug Induced Dyskinesia

  • Condition: Multiple Endocrinopathies, Hypercalcemia and Pancreatitis Following Combined Immune Checkpoint Inhibitor (ICI) Use
  • Journal: BMC endocrine disorders
  • Treatment Used: Zoledronic Acid and Oral Prednisolone
  • Number of Patients: 1
  • Published —
This case report describes a 46-year old Caucasian female with malignant melanoma and lung metastases who developed multiple endocrinopathies, hypercalcemia, and pancreatitis following combined immune checkpoint inhibitor use treated with zoledronic acid and oral prednisolone.
  • Condition: Myelitis from Immune Checkpoint Inhibitors
  • Journal: Neurology(R) neuroimmunology & neuroinflammation
  • Treatment Used: Glucocorticoids
  • Number of Patients: 7
  • Published —
The study researched the use of glucocorticoids for treating myelitis as a complication of immune checkpoint inhibitors.

Clinical Trials For Drug Induced Dyskinesia

Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 2
  • Intervention Type: Procedure, Biological
  • Participants: 45
  • Start Date: October 2021
A Clinical Research on the Safety/Efficacy of Umbilical Cord Mesenchymal Stem Cells Therapy for Patients With Spinocerebellar Ataxia
Clinical Trial
  • Status: Not yet recruiting
  • Intervention Type: Behavioral
  • Participants: 30
  • Start Date: August 1, 2021
Spectral Analyses of Resting Postural Tremor Measured by Accelerometer and Gyroscope as a Predictive Tool of Multiple Sclerosis