Learn About Arginase Deficiency

View Main Condition: Urea Cycle Disorders (UCD)

What is the definition of Arginase Deficiency?

Arginase deficiency is an inherited disorder that causes the amino acid arginine (a building block of proteins) and ammonia to accumulate gradually in the blood. Ammonia, which is formed when proteins are broken down in the body, is toxic if levels become too high. The nervous system is especially sensitive to the effects of excess ammonia.

Save information for later
Sign Up
What are the causes of Arginase Deficiency?

Mutations in the ARG1 gene cause arginase deficiency.

How prevalent is Arginase Deficiency?

Arginase deficiency is a very rare disorder; it has been estimated to occur once in every 300,000 to 1,000,000 individuals.

Is Arginase Deficiency an inherited disorder?

This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

Who are the top Arginase Deficiency Local Doctors?
Learn about our expert tiers
Learn more
What are the latest Arginase Deficiency Clinical Trials?
Match to trials
Find the right clinical trials for you in under a minute
Get started
Who are the sources who wrote this article ?

Published Date: August 01, 2013Published By: National Institutes of Health

What are the Latest Advances for Arginase Deficiency?

There is no recent research available for this condition. Please check back because thousands of new papers are published every week and we strive to find and display the most recent relevant research as soon as it is available.