Learn About Asherman Syndrome

What is the definition of Asherman Syndrome?

Asherman syndrome is the formation of scar tissue in the uterine cavity. The problem most often develops after uterine surgery.

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What are the alternative names for Asherman Syndrome?

Uterine synechiae; Intrauterine adhesions; Infertility - Asherman

What are the causes of Asherman Syndrome?

Asherman syndrome is a rare condition. In most cases, it occurs in women who have had several dilatation and curettage (D&C) procedures.

A severe pelvic infection unrelated to surgery may also lead to Asherman syndrome.

Adhesions in the uterine cavity can also form after infection with tuberculosis or schistosomiasis. These infections are rare in the United States. Uterine complications related to these infections are even less common.

What are the symptoms of Asherman Syndrome?

The adhesions may cause:

  • Amenorrhea (lack of menstrual periods)
  • Repeated miscarriages
  • Infertility

However, such symptoms could be related to several conditions. They are more likely to indicate Asherman syndrome if they occur suddenly after a D&C or other uterine surgery.

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What are the current treatments for Asherman Syndrome?

Treatment involves surgery to cut and remove the adhesions or scar tissue. This can most often be done with hysteroscopy. This uses small instruments and a camera placed into the uterus through the cervix.

After scar tissue is removed, the uterine cavity must be kept open while it heals to prevent adhesions from returning. Your health care provider may place a small balloon inside the uterus for several days. You may also need to take estrogen while the uterine lining heals.

You may need to take antibiotics if there is an infection.

Who are the top Asherman Syndrome Local Doctors?
Highly rated in

Vall Hebron Institut De Recerca

Barcelona, CT, ES 

Xavier Santamaria is in Barcelona, Spain. Santamaria is rated as an Elite expert by MediFind in the treatment of Asherman Syndrome. He is also highly rated in 1 other condition, according to our data. His top areas of expertise are Asherman Syndrome, Endometriosis, Uterine Fibroids, and Infertility.

Highly rated in
Obstetrics and Gynecology
Reproductive Medicine

Mass General Brigham

Newton-Wellesley Hospital

2014 Washington St 
Newton, MA 2462

Keith Isaacson is an Obstetrics and Gynecologist and a Reproductive Medicine doctor in Newton, Massachusetts. Dr. Isaacson has been practicing medicine for over 39 years and is rated as an Elite doctor by MediFind in the treatment of Asherman Syndrome. He is also highly rated in 8 other conditions, according to our data. His top areas of expertise are Asherman Syndrome, Uterine Fibroids, Endometriosis, and Adenomyosis. He is licensed to treat patients in Massachusetts. Dr. Isaacson is currently accepting new patients.

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Highly rated in

Instituto De Investigación Sanitaria La Fe

Reproductive Medicine Research Group 
Valencia, VC, ES 46026

Irene Cervello is in Valencia, Spain. Cervello is rated as an Elite expert by MediFind in the treatment of Asherman Syndrome. She is also highly rated in 2 other conditions, according to our data. Her top areas of expertise are Asherman Syndrome, Uterine Fibroids, Adenomyosis, and Bone Marrow Transplant.

What are the support groups for Asherman Syndrome?

The stress of illness can often be helped by joining a support group. In such groups, members share common experiences and problems.

What is the outlook (prognosis) for Asherman Syndrome?

Asherman syndrome can often be cured with surgery. Sometimes more than one procedure will be necessary.

Women who are infertile because of Asherman syndrome may be able to have a baby after treatment. Successful pregnancy depends on the severity of Asherman syndrome and the difficulty of the treatment. Other factors that affect fertility and pregnancy may also be involved.

What are the possible complications of Asherman Syndrome?

Complications of hysteroscopic surgery are uncommon. When they occur, they may include bleeding, perforation of the uterus, and pelvic infection.

In some cases, treatment of Asherman syndrome will not cure infertility.

When should I contact a medical professional for Asherman Syndrome?

Call your provider if:

  • Your menstrual periods do not return after a gynecologic or obstetrical surgery.
  • You cannot get pregnant after 6 to 12 months of trying (See a specialist for an infertility evaluation).
How do I prevent Asherman Syndrome?

Most cases of Asherman syndrome cannot be predicted or prevented.

Normal uterine anatomy (cut section)
What are the latest Asherman Syndrome Clinical Trials?
PREvention of Intrauterine Adhesion After Adhesiolysis With Novel Tri-block deGradable Polymer Film.
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Prevalence of Intrauterine Adhesions After the Application of Hyaluronic Acid Gel After Dilatation and Curettage in Women With Spontaneous Abortion or Induction of Abortion From 12+0 Till 23+6 Week of Pregnancy.
What are the Latest Advances for Asherman Syndrome?
Comparison of effectiveness of hyaluronan gel, intrauterine device and their combination for prevention adhesions in patients after intrauterine surgery: Systematic review and meta-analysis.
Effectiveness, complications and reproductive outcome of selective chemoembolization with methotrexate followed by suction curettage for caesarean scar pregnancy - A prospective observational study.
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Meta-analysis of the use of amniotic membrane to prevent recurrence of intrauterine adhesion after hysteroscopic adhesiolysis.
Who are the sources who wrote this article ?

Published Date: June 08, 2020
Published By: LaQuita Martinez, MD, Department of Obstetrics and Gynecology, Emory Johns Creek Hospital, Alpharetta, GA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Brown D, Levine D. The uterus. In: Rumack CM, Levine D, eds. Diagnostic Ultrasound. 5th ed. Philadelphia, PA: Elsevier; 2018:chap 15.

Dolan MS, Hill C, Valea FA. Benign gynecologic lesions: vulva, vagina, cervix, uterus, oviduct, ovary, ultrasound imaging of pelvic structures. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 18.

Keyhan S, Muasher L, Muasher SJ. Spontaneous abortion and recurrent pregnancy loss: etiology, diagnosis, treatment. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 16.

Williams Z, Scott JR. Recurrent pregnancy loss. In: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Silver RM, eds. Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2019:chap 44.