PCR for Aspergillus Fumigatus in Blood and Bronchoalveolar Lavage Fluid for Monitoring Cases of Invasive Aspergillosis: What is Its Prognostic Value
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Aspergillus fumigatus PCR is currently used in conjunction with serum galactomannan to support the diagnosis of invasive aspergillosis or for monitoring at-risk patients not receiving antifungal prophylaxis. A positive result and a high titer are thought to be associated with the advanced stage of the disease and the fungal load. However, there is limited data on this subject, and no study has primarily focused on the variation of PCR levels during treatment and its potential correlation with treatment efficacy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients aged 18 years or older
• Positive Aspergillus fumigatus PCR on serum or bronchoalveolar lavage fluid at diagnosis, performed at the Strasbourg University Hospital between January 1, 2017, and December 31, 2024.
Locations
Other Locations
France
Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France
RECRUITING
Strasbourg
Contact Information
Primary
baptiste Hoellinger, MD
baptiste.hoellinger@chru-strasbourg.fr
33 3 69 55 05 45
Time Frame
Start Date: 2025-03-17
Estimated Completion Date: 2026-02
Participants
Target number of participants: 100
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Strasbourg, France