Consequences of SARS-CoV2 Pandemic on Childhood Asthma Control and Exacerbations: French Multicenter Cross-sectional VIRASTHMA COVID G4 Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The SARS-CoV2 pandemic, which emerged in the first quarter of 2020, has led to an unprecedented health crisis in our modern healthcare systems and has resulted in strong national public health measures. The impact of the pandemic and its indirect environmental consequences on pediatric asthma is currently being assessed. In particular, the study of its role on the risk of exacerbations and modification of control is one of the priority research objectives defined by European societies. The primary aim is to study the impact of the pandemic on asthma control in children aged 3-16 years with a medical diagnosis of asthma, compared to data from other observational cohorts conducted in the same region prior to the pandemic. A sub-population of children 3-16 years will be assessed at exacerbation and at a follow-up visit, 2-4 months later, with clinical data, biological and microbiological samples.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Maximum Age: 16
Healthy Volunteers: f
View:

• Children and adolescents aged 3 to 16 years old

• With a medical diagnosis of asthma as per-guidelines, who had been followed-up for at least 6 months,

• Assessed in one of the pediatric departments participating in the study,

• After written consent of at least one of the 2 parents and/or representative of the parental authority, and of the child if he is older than 8 years old.

⁃ Criteria for the sub-population assessed at exacerbation and second visit:

• Children and adolescents aged 3 to 16 years

• With a medical diagnosis of asthma as per-guidelines, who had been followed-up for at least 6 months,

• Hospitalized for a severe asthma exacerbation (requiring hospitalization and general corticosteroid therapy) at Lille University Hospital

• After written consent of both parents and/or representative of the parental authority, and of the child if he is over 8 years old

Locations
Other Locations
France
CHU Lille
RECRUITING
Lille
Contact Information
Primary
Stéphanie Lejeune, MD
stephanie.lejeune@chru-lille.fr
0320445962
Time Frame
Start Date: 2021-09-14
Estimated Completion Date: 2025-07
Participants
Target number of participants: 577
Treatments
Group 1
population included in the VIRASTHMA COVID G4 study
Group 2
population included in the previous studies VIRASTHMA, CHAMPIASTHMA (IRDCB No.: 2019-A03310-57), COBRAPED (NCT02114034), VIRASTHMA 2 (IRDCB No.: 2014 A01687 40, NCT: 03960359), INCOVPED (pediatric emergencies, NCT04336761).
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Lille

This content was sourced from clinicaltrials.gov

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