5HTP Regulation Of Asthma In Children
The purpose of this study is to learn more about if taking a supplement called 5-hydroxytryptophan (5HTP) can improve breathing and anxiety symptoms related to asthma. To help learn more subjects will either be assigned to a group that is taking the supplement (5HTP) or a group that is taking a placebo. This will be decided randomly. Later in the study subjects will crossover to the other group.There are 5 study visits over the course of about 12 weeks.
• Age 8-18 Years of Age
• Mild to Moderate Asthma based on ATS guidelines
• Positive Allergy Test (positive skin or serum IgE)
• Weight ≥ 70 lbs (32 kg)
• CES-DC cut-off ≥ 15 (total score range is 0 to 60) or SCARED cut-off
⁃ 25 (total score range is 0 to 142)
• Ability to comply with study visits and study procedures
• Informed Consent by participant and if applicable the parent or legal guardian