Pollution Intervention to Impact Kids Asthma Study

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are: * Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time? * Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution? Researchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma. Participants will: * Receive standardized outdoor air pollution education and an asthma action plan * Provide nose and blood specimens * Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 8
Maximum Age: 17
Healthy Volunteers: f
View:

• A healthcare provider diagnosis of persistent asthma (Steps 2-5 as defined by US guidelines) or intermittent asthma (Step 1) + at least one severe asthma exacerbation (defined by American Thoracic Society (ATS)/European Respiratory Society (ERS) criteria as requiring at least 3 days of systemic steroids or an Emergency Department/Urgent Care visit requiring systemic steroids) in the prior 12 months

• Home access to a smartphone or internet

• Primary residence in Allegheny County, PA

• One participant per household

• Age 8 -17 years

• Healthcare provider evaluation for asthma in the prior year

Locations
United States
Pennsylvania
UPMC Children's Hospital of Pittsburgh
RECRUITING
Pittsburgh
Contact Information
Primary
Pediatric Asthma Center
franziska.rosser2@chp.edu
877-296-9026
Time Frame
Start Date: 2026-02
Estimated Completion Date: 2030-01
Participants
Target number of participants: 351
Treatments
Active_comparator: Control (Standard outdoor air pollution education + asthma action plan)
Control
Experimental: EPA-AQI (Education+ plan + EPA-AQI)
EPA-AQI
Experimental: Commercial-AQI (Education+ plan + commercial-AQI)
Commercial-AQI
Related Therapeutic Areas
Sponsors
Leads: University of Pittsburgh
Collaborators: National Institute of Environmental Health Sciences (NIEHS)

This content was sourced from clinicaltrials.gov