Interest of Forced Oscillations During a Methacholine Test in Children

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Asthma is the most common chronic lung disease in children. It affects more than 1 in 10 children in France. The methacholine bronchial challenge test (MBT) is indicated to assess the probability of asthma suggested by clinical symptoms by measuring the forced expiratory volume in one second (FEV1), after inhalation of a cumulative dose of methacholine. In children, the measurement of FEV1 requires a high level of cooperation from the child, which can be the source of false negatives or no result if this is not obtained. The objective of this study is to evaluate if the measurement of the respiratory function by the forced oscillations technique, allows to predict the variation of the FEV1 obtained

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6
Maximum Age: 16
Healthy Volunteers: f
View:

• Age between 6 and 16 years

• FEV1 \> 60%

• Child referred to the pulmonary function test laboratory for a non-specific bronchial hyperactivity test with methacholine

• Child under treatment with inhaled corticosteroids stopped for at least 3 weeks

• Oral consent from the child and at least one of the legal representatives

• Child affiliated or benefiting from a social security plan

Locations
Other Locations
France
CHU de Montpellier
RECRUITING
Montpellier
Contact Information
Primary
Stefan MATECKI, MD
Stephan.matecki@umontpellier.fr
+33 4 67 33 59 12
Backup
Anne REQUIRAND
a-requirand@chu-montpellier.fr
Time Frame
Start Date: 2023-09-07
Estimated Completion Date: 2026-12-30
Participants
Target number of participants: 112
Treatments
Other: Single Arm
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Montpellier

This content was sourced from clinicaltrials.gov

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