Is Clonal Hematopoiesis of Indeterminate Potential Associated With Unprovoked Pulmonary Embolism?
Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The clonal hematopoiesis of indetermined prognosis (CHIP) has been described as risk factor for juvenile atherosclerosis. Moreover, some of CHIP genes are responsible of myeloproliferative disorders. Venous thrombosis are frequent in these disorders. The purpose of this project is to determine if CHIP is frequent in unprovoked pulmonary embolism and could be part of the pathophysiology.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• For cases : Previous proximal unprovoked pulmonary embolism, negative thrombophilia screening.
• For control : Previous proximal provoked pulmonary embolism, negative thrombophilia screening.
Locations
Other Locations
France
CHU Amiens
RECRUITING
Amiens
Contact Information
Primary
Simon SOUDET, MD
soudet.simon@chu-amiens.fr
03 22 88 72 89
Time Frame
Start Date: 2021-02-01
Estimated Completion Date: 2026-01
Participants
Target number of participants: 544
Treatments
Experimental: Previous proximal unprovoked pulmonary embolism
Active_comparator: Previous proximal provoked pulmonary embolism
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire, Amiens