MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology
In our research, we are delving into whether taking MitoQ for six months can improve the symptoms and function of people diagnosed with peripheral artery disease, especially those who suffer from leg pain while walking, known as intermittent claudication. We will be checking if MitoQ helps people with claudication walk better, be more active every day, feel better about their lives, and if it enhances the health of their leg muscles.
• a positive history of chronic claudication
• exercise-limiting claudication established by history and direct observation during a screening walking test administered by the evaluating vascular surgeon
• documented lower extremity arterial occlusive disease based on ankle/brachial index measurements and/or arterial imaging
• stable blood pressure, lipid and diabetes regimens and risk factor control for 6 weeks.