Peripheral Artery Disease
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Peripheral Artery Disease Overview

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Learn About Peripheral Artery Disease

What is the definition of Peripheral Artery Disease?
Peripheral artery disease is a condition in which the blood flow to the limbs is reduced due to a narrowing or blockage of the arteries. This narrowing of the arteries is usually caused by fatty buildup (plaque) called atherosclerosis. Peripheral artery disease more commonly affects the legs but may also occur in the arms.
What are the symptoms of Peripheral Artery Disease?
Peripheral artery disease may not have any symptoms or only mild symptoms. The most common symptoms of peripheral artery disease are mild-to-severe leg pain or cramping (claudication). Claudication is most often felt in the calf upon walking or climbing stairs and stops when at rest. Other symptoms of peripheral artery disease include cramping in one or both hips; leg numbness or weakness; cold lower legs and feet; sores or ulcerations on legs, feet, or toes that won’t heal; a bluish or grayish limb skin color; leg muscle wasting; slow hair growth or hair loss on legs; slow toenail growth; weak or absent pulse in legs or feet; pain when using arms such as when writing or doing manual work; and erectile dysfunction in men. Severe peripheral artery disease may also cause pain at rest and interrupt sleep.
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What are the current treatments for Peripheral Artery Disease?
Early peripheral artery disease can often be treated with exercise, a healthy diet, and quitting smoking. Treatment for more advanced peripheral artery disease is focused on managing pain and stopping atherosclerosis to prevent blood clots, heart attack, and stroke. Treatments for peripheral artery disease include regular exercise and medications, such as cholesterol-lowering drugs (statins); blood pressure-lowering drugs; blood sugar-lowering drugs; anticoagulant drugs to prevent blood clots, such as aspirin and Plavix; and drugs that increase blood flow to the limbs, such as cilostazol or pentoxifylline. Treatments for peripheral artery disease that is causing claudication include angioplasty, in which a catheter is inserted with a stent to reopen an artery and increase blood flow; and bypass surgery, in which an artery taken from another area of the body, or a synthetic vessel, is grafted around a blocked artery. Thrombolytic therapy, in which a clot-dissolving drug is injected into a blocked artery, may also be used to treat peripheral artery disease that has caused blood clots.
Who are the top Peripheral Artery Disease Local Doctors?
Jeffrey Berger
Elite in Peripheral Artery Disease
Dr. Jeffrey Berger
Cardiology
Elite in Peripheral Artery Disease
Dr. Jeffrey Berger
Cardiology

New York University

530 1st Ave # 5, 
New York, NY 
212-263-0855
Languages Spoken:
English
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Jeffrey Berger is a Cardiologist in New York, New York. Dr. Berger is rated as an Elite provider by MediFind in the treatment of Peripheral Artery Disease. His top areas of expertise are Peripheral Artery Disease, Atherosclerosis, Carotid Artery Disease, Percutaneous Coronary Intervention (PCI), and Heart Bypass Surgery.

Manesh R. Patel
Elite in Peripheral Artery Disease
Dr. Manesh R. Patel
Cardiology
Elite in Peripheral Artery Disease
Dr. Manesh R. Patel
Cardiology

Duke Cardiology Arringdon

5601 Arringdon Park Dr, 
Morrisville, NC 
919-997-3100
Experience:
29+ years
Languages Spoken:
English, Gujarati 
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Offers Telehealth

I am an interventional cardiologist and researcher who has been at Duke for nearly 20 years. I enjoy being at Duke because of the “family” I get to work with every day. When we are able to make a patient feel better through teamwork; it’s a great feeling. I chose cardiology as my specialty because of the chance to make a difference in someone’s life in real time. When someone is having a heart attack, they are relying on you to come to their aid quickly. At that moment, I get to apply science to save a life, while learning more about what we can do to help improve people’s lives in the future. In that way, medicine also gives me the chance to learn from my patients and apply what I find to benefit the greater good. I find that whole process is exciting. When I am not at work, I enjoy spending time with my school-aged children. Dr. Patel is rated as an Elite provider by MediFind in the treatment of Peripheral Artery Disease. His top areas of expertise are Peripheral Artery Disease, Atherosclerosis, Coronary Heart Disease, Percutaneous Coronary Intervention (PCI), and Angioplasty.

 
 
 
 
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Subhash Banerjee
Elite in Peripheral Artery Disease
Dr. Subhash Banerjee
Interventional Cardiology | Cardiology
Elite in Peripheral Artery Disease
Dr. Subhash Banerjee
Interventional Cardiology | Cardiology

Baylor Scott & White Cardiology Consultants Of Texas - Dallas

621 N Hall St, Ste 500, 
Dallas, TX 
469-800-7400
Languages Spoken:
English
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Offers Telehealth

As a board-certified interventional cardiologist, Dr. Banerjee is internationally recognized for his expertise in minimally invasive treatments of coronary artery disease, peripheral artery disease and transcatheter aortic valve replacement. He is currently serving as the Paul J. Thomas Endowed Chair in Cardiology and chief of cardiovascular research and innovation for Baylor Scott & White Heart and Vascular Services-Dallas. Dr. Banerjee is the editor-in-chief of the American Journal of Cardiology, one of the premier cardiology journals in the world. He also serves as one of the founding directors of the Cardiovascular Innovations Foundation. He has led many landmark clinical trials, published over 450 peer-reviewed manuscripts, and is an invited faculty at national and international cardiovascular conferences. Dr. Banerjee is rated as an Elite provider by MediFind in the treatment of Peripheral Artery Disease. His top areas of expertise are Peripheral Artery Disease, Atherosclerosis, Coronary Heart Disease, Atherectomy, and Percutaneous Coronary Intervention (PCI).

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What are the latest Peripheral Artery Disease Clinical Trials?
Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia: The PROMISE III Trial
Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia: The PROMISE III Trial
Enrollment Status: Recruiting
Publish Date: April 16, 2026
Intervention Type: Device
Study Phase: Not Applicable

Summary: A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.

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ENhancing Exercise With LIGHT to Improve Functioning in PAD: the ENLIGHTEN PAD Trial
ENhancing Exercise With LIGHT to Improve Functioning in PAD: the ENLIGHTEN PAD Trial
Enrollment Status: Recruiting
Publish Date: April 15, 2026
Intervention Type: Device, Behavioral
Study Phase: Not Applicable

Summary: The ENLIGHTEN PAD Trial will collect preliminary data to test whether daily 660 nm light treatment of the lower extremities immediately before home-based walking exercise sessions improves six-minute walk distance at 4-month follow-up, compared to sham light, in people with lower extremity peripheral artery disease (PAD).

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