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Association of Cardiovascular Disease Risk Assessment With Coronary Artery Calcium Score in Thai Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Metabolic dysfunction-associated steatotic liver disease (MASLD) is common in Thailand and is strongly linked to metabolic risk factors such as obesity, diabetes, hypertension, and dyslipidemia. Cardiovascular disease is the leading cause of death among patients with MASLD. Coronary artery calcium (CAC) scoring is a widely used marker of subclinical coronary atherosclerosis. This study aims to evaluate the association between cardiovascular risk assessment tools and CAC scores in Thai patients with MASLD to improve cardiovascular risk stratification in this population.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 35
Maximum Age: 75
Healthy Volunteers: t
View:

• Asymptomatic

• Diagnosed MASLD by: Ultrasound showing fatty liver, or FibroScan CAP ≥ 248 dB/m

• Available liver fibrosis assessment (FIB-4, APRI)

• Complete clinical and laboratory data required for cardiovascular risk assessment

Locations
Other Locations
Thailand
Faculty of Medicine Siriraj Hospital, Mahidol University
RECRUITING
Bangkok
Contact Information
Primary
Assoc. Prof. Watcharasak Chotiyaputta, M.D.
watcharasak.cho@mahidol.ac.th
+66 85-125-5489
Time Frame
Start Date: 2026-06-24
Estimated Completion Date: 2036-06-23
Participants
Target number of participants: 251
Treatments
MASLD Cohort
Thai adult patients diagnosed with metabolic dysfunction-associated steatotic liver disease (MASLD) who underwent coronary artery calcium (CAC) scoring at Siriraj Hospital. Clinical, metabolic, liver disease severity, and CAC score data are collected to evaluate the association between cardiovascular risk assessment tools and coronary calcification.
Sponsors
Leads: Watcharasak Chotiyaputta

This content was sourced from clinicaltrials.gov