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Condition

Obesity

Symptoms, Doctors, Treatments, Research & More

Condition 101

What is the definition of Obesity?

Obesity means having too much body fat. It is not the same as being overweight, which means weighing too much. A person may be overweight from extra muscle or water, as well as from having too much fat.

Both terms mean that a person's weight is higher than what is thought to be healthy for his or her height.

What are the alternative names for Obesity?

Morbid obesity; Fat - obese

What are the causes for Obesity?

Taking in more calories than your body burns can lead to obesity. This is because the body stores unused calories as fat. Obesity can be caused by:

  • Eating more food than your body can use
  • Drinking too much alcohol
  • Not getting enough exercise

Many obese people who lose large amounts of weight and gain it back think it is their fault. They blame themselves for not having the willpower to keep the weight off. Many people regain more weight than they lost.

Today, we know that biology is a big reason why some people cannot keep the weight off. Some people who live in the same place and eat the same foods become obese, while others do not. Our bodies have a complex system to keep our weight at a healthy level. In some people, this system does not work normally.

The way we eat when we are children can affect the way we eat as adults.

The way we eat over many years becomes a habit. It affects what we eat, when we eat, and how much we eat.

We may feel that we are surrounded by things that make it easy to overeat and hard to stay active.

  • Many people feel they do not have time to plan and make healthy meals.
  • More people today work desk jobs compared to more active jobs in the past.
  • People with little free time may have less time to exercise.

The term eating disorder means a group of medical conditions that have an unhealthy focus on eating, dieting, losing or gaining weight, and body image. A person may be obese, follow an unhealthy diet, and have an eating disorder all at the same time.

Sometimes, medical problems or treatments cause weight gain, including:

  • Underactive thyroid (hypothyroidism)
  • Medicines such as birth control pills, antidepressants, and antipsychotics

Other things that can cause weight gain are:

  • Quitting smoking -- Many people who quit smoking gain 4 to 10 pounds (lb) or 2 to 5 kilograms (kg) in the first 6 months after quitting.
  • Stress, anxiety, feeling sad, or not sleeping well.
  • Menopause -- Women may gain 12 to 15 lb (5.5 to 7 kg) during menopause.
  • Pregnancy -- Women may not lose the weight they gained during pregnancy.
Childhood

What are the current treatments for Obesity?

CHANGING YOUR LIFESTYLE

An active lifestyle and plenty of exercise, along with healthy eating, is the safest way to lose weight. Even modest weight loss can improve your health. You may need a lot of support from family and friends.

Your main goal should be to learn new, healthy ways of eating and make them part of your daily routine.

Many people find it hard to change their eating habits and behaviors. You may have practiced some habits for so long that you may not even know they are unhealthy, or you do them without thinking. You need to be motivated to make lifestyle changes. Make the behavior change part of your life over the long term. Know that it takes time to make and keep a change in your lifestyle.

Work with your provider and dietitian to set realistic, safe daily calorie counts that help you lose weight while staying healthy. Remember that if you drop weight slowly and steadily, you are more likely to keep it off. Your dietitian can teach you about:

  • Healthy food choices at home and in restaurants
  • Healthy snacks
  • Reading nutrition labels and healthy grocery shopping
  • New ways to prepare food
  • Portion sizes
  • Sweetened drinks

Extreme diets (fewer than 1,100 calories per day) are not thought to be safe or to work very well. These types of diets often do not contain enough vitamins and minerals. Most people who lose weight this way return to overeating and become obese again.

Learn ways to manage stress other than snacking. Examples may be meditation, yoga, or exercise. If you are depressed or stressed a lot, talk to your provider.

MEDICINES AND HERBAL REMEDIES

You may see ads for supplements and herbal remedies that claim they will help you lose weight. Some of these claims may not be true. And some of these supplements can have serious side effects. Talk to your provider before using them.

You can discuss weight loss medicines with your provider. Many people lose at least 5 lb (2 kg) by taking these drugs, but they may regain the weight when they stop taking the medicine unless they have made lifestyle changes.

SURGERY

Bariatric (weight-loss) surgery can reduce the risk of certain diseases in people with severe obesity. These risks include:

  • Arthritis
  • Diabetes
  • Heart disease
  • High blood pressure
  • Sleep apnea
  • Some cancers
  • Stroke

Surgery may help people who have been very obese for 5 years or more and have not lost weight from other treatments, such as diet, exercise, or medicine.

Surgery alone is not the answer for weight loss. It can train you to eat less, but you still have to do much of the work. You must be committed to diet and exercise after surgery. Talk to your provider to learn if surgery is a good option for you.

Weight-loss surgeries include:

  • Laparoscopic gastric banding
  • Gastric bypass surgery
  • Sleeve gastrectomy
  • Duodenal switch

What are the support groups for Obesity?

Many people find it easier to follow a diet and exercise program if they join a group of people with similar problems.

More information and support for people with obesity and their families can be found at: Obesity Action Coalition -- www.obesityaction.org/community/find-support-connect/find-a-support-group/.

What are the possible complications for Obesity?

Obesity is a major health threat. The extra weight creates many risks to your health.

REFERENCES

Cowley MA, Brown WA, Considine RV. Obesity: the problem and its management. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 26.

Jensen MD. Obesity. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 207.

Jensen MD, Ryan DH, Apovian CM, et al; American College of Cardiology/American Heart Association Task Force on Practice Guidelines; Obesity Society. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation. 2014;129 (25 Suppl 2):S102-S138. PMID: 24222017 pubmed.ncbi.nlm.nih.gov/24222017/.

Oh TJ. The role of anti-obesity medication in prevention of diabetes and its complications. J Obes Metab Syndr. 2019;28(3):158-166. PMID: 31583380 pubmed.ncbi.nlm.nih.gov/31583380/.

Pilitsi E, Farr OM, Polyzos SA, et al. Pharmacotherapy of obesity: available medications and drugs under investigation. Metabolism. 2019;92:170-192. PMID: 30391259 pubmed.ncbi.nlm.nih.gov/30391259/.

Raynor HA, Champagne CM. Position of the Academy of Nutrition and Dietetics: interventions for the treatment of overweight and obesity in adults. J Acad Nutr Diet. 2016;116(1):129-147. PMID: 26718656 pubmed.ncbi.nlm.nih.gov/26718656/.

Richards WO. Morbid obesity. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 20th ed. Philadelphia, PA: Elsevier: 2017:chap 47.

Ryan DH, Kahan S. Guideline Recommendations for obesity management. Med Clin North Am. 2018;102(1):49-63. PMID: 29156187 pubmed.ncbi.nlm.nih.gov/29156187/.

Semlitsch T, Stigler FL, Jeitler K, Horvath K, Siebenhofer A. Management of overweight and obesity in primary care-A systematic overview of international evidence-based guidelines. Obes Rev. 2019;20(9):1218-1230. PMID: 31286668 pubmed.ncbi.nlm.nih.gov/31286668/.

Latest Research

Latest Advance
Study
  • Condition: Non-Small Cell Lung Cancer with PD-L1 Expression
  • Journal: Journal for immunotherapy of cancer
  • Treatment Used: Pembrolizumab
  • Number of Patients: 1388
  • Published —
This study investigated the association between obesity and clinical outcomes in patients undergoing first-line pembrolizumab therapy for their non-small cell lung cancer with PD-L1 expression greater than 50%.
Latest Advance
Study
  • Condition: Older Adults with Metabolic Syndrome (MetS)
  • Journal: Nutrients
  • Treatment Used: Resveratrol, Piperine, and Alpha-Tocopherol
  • Number of Patients: 0
  • Published —
This study evaluated the effectiveness of supplementation with resveratrol, piperine, and alpha-tocopherol in older adults with metabolic syndrome (cluster of conditions that occur together, increasing the risk of heart disease, stroke and type 2 diabetes; MetS).

Clinical Trials

Clinical Trial
Behavioral
  • Status: Not yet recruiting
  • Study Type: Behavioral
  • Participants: 300
  • Start Date: April 2022
Community Active and Healthy Families: Family-Centered Obesity Treatment for Latino Children
Clinical Trial
Other
  • Status: Not yet recruiting
  • Study Type: Other
  • Participants: 100
  • Start Date: January 1, 2022
Maternal Obesity Programs Offspring Hypothalamic Neurogenesis and Appetite: Mechanisms and Prevention of Hyperphagia-mediated Childhood Obesity