The Effects of Diet and Exercise Interventions in Peripheral Artery Disease
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study is a 3-month, prospective, randomized controlled clinical trial designed to address the efficacy of the DASH dietary program combined with a home-based exercise program, quantified by a step activity monitor, to improve exercise and vascular outcome measures in patients with PAD.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:
• History of claudication,
• Presence of PAD, defined by meeting at least one of the following criteria (ABI at rest \< 0.90, or \> 20% decrease in ABI following a heel-rise exercise test in patients with a normal ABI at rest (\> 0.90), or history of peripheral revascularization.
Locations
United States
Oklahoma
O'Donoghue Research Building, University of Oklahoma Health Sciences Center
RECRUITING
Oklahoma City
Contact Information
Primary
Andrew Gardner, Ph.D.
andrew-gardner@ouhsc.edu
405-271-4742
Time Frame
Start Date: 2024-09-16
Estimated Completion Date: 2029-05-31
Participants
Target number of participants: 150
Treatments
Experimental: DASH Diet plus Home-Based Exercise
The DASH dietary program consists of a diet emphasizing foods rich in fruits, vegetables, whole grains, and low-fat dairy, in which patients record daily servings of fruits and vegetables. The home-based exercise program consists of intermittent walking to moderate claudication pain 3 times per week for 3 months in a home-based setting.
Active_comparator: Home-Based Exercise
The home-based exercise program consists of intermittent walking to moderate claudication pain 3 times per week for 3 months in a home-based setting.
Related Therapeutic Areas
Sponsors
Collaborators: Milton S. Hershey Medical Center, National Institute on Aging (NIA), Case Western Reserve University
Leads: University of Oklahoma