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Condition

Atrophoderma of Pierini and Pasini

Symptoms, Doctors, Treatments, Research & More

Condition 101

What is the definition of Atrophoderma of Pierini and Pasini?

Atrophoderma of Pasini and Pierini (ATPP) is a rare skin condition that results in patchy areas of discolored skin. The main symptom of atrophoderma of Pasini and Pierini is multiple irregularly shaped, dark or light areas of skin in which the tissue under the skin breaks down resulting in a de ...

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What are the alternative names for Atrophoderma of Pierini and Pasini?

  • Idiopathic atrophoderma of Pasini and Pierini
  • Congenital atrophoderma of Pasini and Pierini

What are the causes for Atrophoderma of Pierini and Pasini?

The cause of atrophoderma of Pasini and Pierini is unknown. In some cases, a bacteria known as Borrelia burgdorferi may be the cause. In others, a possible genetic cause is suspected. 

What are the symptoms for Atrophoderma of Pierini and Pasini?

The following list includes the most common signs and symptoms in people with atrophoderma of Pasini and Pierini. These features may be different from person to person. Some people may have more symptoms than others and symptoms can range from mild to severe. This list does not include every symptom or feature that has been described in this condition.

The main symptom of atrophoderma of Pasini and Pierini is dark or light-colored indented areas of skin with irregular shapes and borders. Some people have pain, itching, or numbness associated with the skin findings. 

The skin findings in this condition usually appear in adolescence or early adulthood. The trunk is usually affected first and then the changes in the skin may spread to the chest, arms and stomach. Atrophoderma of Pasini and Pierini may progress over 10-20 years and then stops.  Very rarely, this condition will progress to systemic sclerosis. 

What are the current treatments for Atrophoderma of Pierini and Pasini?

There is no specific treatment for atrophoderma of Pasini and Pierini.  Treatments that have been tried with some success include antibiotics, topical medications, anti-malarial drugs, and laser treatments.

Specialists who may be involved in the care of someone with atrophoderma of Pasini and Pierini include:
  • Dermatologist
  • Pharmacist

How is Atrophoderma of Pierini and Pasini diagnosed?

Atrophoderma of Pasini and Pierini is diagnosed based on a clinical examination and a skin biopsy to look at a piece of affected skin under the microscope.

Latest Research

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Clinical Trials

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