Attention Deficit Hyperactivity Disorder (ADHD) Clinical Trials

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Effects of Transcranial Photobiomodulation on Cognition and Brain Metabolism in Adults With ADHD

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The investigators have previously shown that non-invasive methods of brain stimulation such as the administration of transcranial infrared light to the prefrontal cortex (PFC) can result in improvements to cognition and emotion as well as brain oxygenation. This method is called transcranial photobiomodulation (tPBM). The investigators hypothesize that tPBM can improve cognition and brain oxygenation in adults with attention deficit hyperactivity disorder (ADHD). The investigators will investigate the effects of repeated tPBM sessions on cognitive functioning in adults with ADHD. Specifically, the investigators hypothesize that participants that receive tPBM will show improvements in response control, sustained attention, and working memory, as well as improvements in prefrontal hemodynamics and a reduction in ADHD symptoms.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 44
Healthy Volunteers: f
View:

• English-speaking

• Adults of any sex

• Age range: 18-44 years

• Any ethnic/racial background

• Medical history of ADHD

• Participants may either be on a stable ADHD medication regimen (with no changes within two weeks prior to the study) or not taking medication.

Locations
United States
Texas
The University of Texas at Austin
RECRUITING
Austin
Contact Information
Primary
Francisco Gonzalez-Lima, Ph.D.
UTBrainProject@gmail.com
512-537-5257
Time Frame
Start Date: 2025-09-01
Estimated Completion Date: 2027-12
Participants
Target number of participants: 140
Treatments
Active_comparator: Active transcranial photobiomodulation
Participants in this arm will receive active transcranial photobiomodulation to the forehead, targeting prefrontal cortex.
Sham_comparator: Sham transcranial photobiomodulation
Participants in this arm will undergo this same procedure as the active group, but with no 1064-nm light emitted by the device.
Sponsors
Leads: University of Texas at Austin

This content was sourced from clinicaltrials.gov