Attenuated Familial Adenomatous Polyposis Overview

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Learn About Attenuated Familial Adenomatous Polyposis

What is the definition of Attenuated Familial Adenomatous Polyposis?
Attenuated familial adenomatous polyposis (AFAP) is an inherited condition that increases the chance to develop cancer of the large intestine (colon) and rectum. It is a milder form of classic familial adenomatous polyposis (FAP). SYmptom may include colon polyps, benign or malignant tumors of the duodenum (a section of the small intestine) and, in rare cases, other symptoms of FAP. AFAP is caused by genetic changes in the APC gene and is inherited in an autosomal dominant manner.
What are the alternative names for Attenuated Familial Adenomatous Polyposis?
  • Attenuated familial adenomatous polyposis
  • AAPC
  • AFAP
  • Attenuated FAP
  • Attenuated adenomatous polyposis coli
  • Attenuated familial polyposis coli
  • Mild form of FAP
Who are the top Attenuated Familial Adenomatous Polyposis Local Doctors?
Dr. Hal G. Fiser
General Surgery
Dr. Hal G. Fiser
General Surgery

Central Surgical Associates

1190 N State St, Suite 502, 
Jackson, MS 
 1.1 mi
Accepting New Patients
Languages Spoken English

Hal Fiser is a General Surgeon in Jackson, Mississippi. Dr. Fiser and is rated as an Experienced provider by MediFind in the treatment of Attenuated Familial Adenomatous Polyposis. His top areas of expertise are Gallbladder Disease, Cholecystitis, Breast Cancer, Lymphadenectomy, and Colostomy. Dr. Fiser is currently accepting new patients.

Dr. George T. Smith-Vaniz
Gastroenterology | Internal Medicine
Dr. George T. Smith-Vaniz
Gastroenterology | Internal Medicine
1860 Chadwick Dr Ste 102, 
Jackson, MS 
 2.0 mi
Accepting New Patients
Offers Telehealth
Languages Spoken English

George Smith-Vaniz is an Internal Medicine provider in Jackson, Mississippi. Dr. Smith-Vaniz and is rated as an Experienced provider by MediFind in the treatment of Attenuated Familial Adenomatous Polyposis. His top areas of expertise are Gastrointestinal Bleeding, Chronic Erosive Gastritis, Diverticular Disease, Gastrostomy, and Endoscopy. Dr. Smith-Vaniz is currently accepting new patients.

 
 
 
 
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Dr. Shou J. Tang
Gastroenterology
Dr. Shou J. Tang
Gastroenterology

State Of Mississippi - University Of Mississippi Medical Center

2500 N State St, 
Jackson, MS 
 2.3 mi
Accepting New Patients
Offers Telehealth
Languages Spoken English

Shou Tang is a Gastroenterologist in Jackson, Mississippi. Dr. Tang and is rated as an Experienced provider by MediFind in the treatment of Attenuated Familial Adenomatous Polyposis. His top areas of expertise are Familial Colorectal Cancer, Bile Duct Obstruction, Childhood Pancreatitis, Endoscopy, and Gastrectomy. Dr. Tang is currently accepting new patients.

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What are the latest Attenuated Familial Adenomatous Polyposis Clinical Trials?
A Phase IIa, Placebo-Controlled, Randomized Study of Daily Obeticholic Acid (OCA) to Reduce Intestinal Polyp Burden in Familial Adenomatous Polyposis (FAP)
A Phase IIa, Placebo-Controlled, Randomized Study of Daily Obeticholic Acid (OCA) to Reduce Intestinal Polyp Burden in Familial Adenomatous Polyposis (FAP)
Who is this study for: Patients with familial adenomatous polyposis
Enrollment Status: Recruiting
Publish Date: December 27, 2024
Intervention Type: Biological, Drug, Procedure, Other
Study Drug: Obeticholic Acid
Study Phase: Phase 2

Summary: This phase IIa trial investigates if giving obeticholic acid (OCA) is safe and has a beneficial effect on the number of polyps in the small bowel and colon in patients with familial adenomatous polyposis (FAP). FAP is a rare gene defect that increases the risk of developing cancer of the intestines and colon. OCA is a drug similar to a bile acid the body makes. It is fluid made and released by the...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center