Learn About Atypical Hemolytic Uremic Syndrome (aHUS)

What is the definition of Atypical Hemolytic Uremic Syndrome (aHUS)?
Atypical hemolytic uremic syndrome is a very rare disease that causes anemia due to red blood cell destruction, a low platelet count, blood clots, and acute kidney failure.
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What are the symptoms of Atypical Hemolytic Uremic Syndrome (aHUS)?
Symptoms of atypical hemolytic uremic syndrome include a sudden onset, malaise, fatigue, lethargy, irritability, anemia, a low platelet count, acute kidney failure, high blood pressure, reduced blood flow and/or small blood clots in blood vessels, headaches, seizures, organ damage and failure, an enlarged heart, heart attack, gastrointestinal bleeding, swelling in the lungs, double vision, facial paralysis, stroke, and coma.
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What are the current treatments for Atypical Hemolytic Uremic Syndrome (aHUS)?
Treatments for atypical hemolytic uremic syndrome include supportive care; nutritional therapy; blood transfusions; peritoneal dialysis or hemodialysis; plasma therapy; plasma exchange; medications, such as vasodilators, eculizumab, ravulizumab-cwvz, and immunosuppressants; and kidney transplantation.
Who are the top Atypical Hemolytic Uremic Syndrome (aHUS) Local Doctors?
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What are the latest Atypical Hemolytic Uremic Syndrome (aHUS) Clinical Trials?
Single Arm Study of ALXN1210 in Complement Inhibitor Treatment-naïve Adult and Adolescent Patients With Atypical Hemolytic Uremic Syndrome (aHUS)
Summary: The purpose of the study is to assess the safety and efficacy of ravulizumab to control disease activity in adolescent and adult participants with aHUS who had not previously used a complement inhibitor.
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Coordination of Rare Diseases at Sanford
Summary: CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, in...
What are the Latest Advances for Atypical Hemolytic Uremic Syndrome (aHUS)?
Could plasma based therapies still be considered in selected cases with atypical hemolytic uremic syndrome?
Summary: Could plasma based therapies still be considered in selected cases with atypical hemolytic uremic syndrome?
Case Report: Combined Liver-Kidney Transplantation to Correct a Mutation in Complement Factor B in an Atypical Hemolytic Uremic Syndrome Patient.
Summary: Case Report: Combined Liver-Kidney Transplantation to Correct a Mutation in Complement Factor B in an Atypical Hemolytic Uremic Syndrome Patient.
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Coexistence of Anti Neutrophilic Cytoplasmic Antibody (ANCA) Negative Renal Limited Vasculitis and Atypical- Hemolytic Uremic Syndrome (aHUS).
Summary: Coexistence of Anti Neutrophilic Cytoplasmic Antibody (ANCA) Negative Renal Limited Vasculitis and Atypical- Hemolytic Uremic Syndrome (aHUS).