Autism spectrum disorder (ASD) is a developmental disorder. It often appears in the first 3 years of life. ASD affects the brain's ability to develop normal social and communication skills.
Autism; Autistic disorder; Asperger syndrome; Childhood disintegrative disorder; Pervasive developmental disorder
The exact cause of ASD isn't known. It's likely that a number of factors lead to ASD. Research shows that genes may be involved, since ASD runs in some families. Certain medicines taken during pregnancy may also lead to ASD in the child.
Other causes have been suspected, but not proven. Some scientists believe that damage to a part of the brain, called the amygdala, may be involved. Others are looking at whether a virus may trigger symptoms.
Some parents have heard that vaccines may cause ASD. But studies have found no link between vaccines and ASD. All expert medical and government groups state that there is no link between vaccines and ASD.
The increase in children with ASD may be due to better diagnosis and newer definitions of ASD. Autism spectrum disorder now includes syndromes that used to be regarded as separate disorders:
Most parents of ASD children suspect that something is wrong by the time the child is 18 months old. Children with ASD often have problems with:
Some children seem normal before age 1 or 2. They then suddenly lose language or social skills they already had.
Symptoms can vary from moderate to severe.
A person with autism may:
Communication problems may include:
Social interaction problems may include:
Response to sensory information problems may include:
Problems with play may include:
Behaviors may include:
At this time, there is no cure for ASD. A treatment program will greatly improve the outlook for most young children. Most programs build on the interests of the child in a highly structured schedule of constructive activities.
Treatment plans may combine techniques, including:
APPLIED BEHAVIORAL ANALYSIS (ABA)
This program is for younger children. It helps in some cases. ABA uses one-on-one teaching that reinforces various skills. The goal is to get the child close to normal functioning for their age.
An ABA program is often done in a child's home. A behavioral psychologist oversees the program. ABA programs can be very expensive and aren't widely used by school systems. Parents often have to find funding and staffing from other sources, which aren't available in many communities.
TEACCH
Another program is called the Treatment and Education of Autistic and Related Communication Handicapped Children (TEACCH). It uses picture schedules and other visual cues. These help children work on their own and organize and structure their environments.
Though TEACCH tries to improve a child's skills and ability to adapt, it also accepts the problems associated with ASD. Unlike ABA programs, TEACCH doesn't expect children to achieve typical development with treatment.
MEDICINES
There is no medicine that treats ASD itself. But medicines are often used to treat behavior or emotional problems that people with ASD may have. These include:
Only the drug risperidone is approved to treat children ages 5 through 16 for the irritability and aggression that can occur with ASD. Other medicines that may also be used are mood stabilizers and stimulants.
DIET
Some children with ASD seem to do well on a gluten-free or casein-free diet. Gluten is in foods containing wheat, rye, and barley. Casein is in milk, cheese, and other dairy products. Not all experts agree that changes in diet make a difference. And not all studies have shown positive results.
If you're thinking about these or other diet changes, talk to both a provider and a registered dietitian. You want to be sure that your child is still getting enough calories and the right nutrients.
OTHER APPROACHES
Beware of widely publicized treatments for ASD that don't have scientific support, and reports of miracle cures. If your child has ASD, talk with other parents. Also discuss your concerns with ASD specialists. Follow the progress of ASD research, which is rapidly developing.
Lonnie Zwaigenbaum practices in Edmonton, Canada. Zwaigenbaum is rated as an Elite expert by MediFind in the treatment of Autism Spectrum Disorder. He is also highly rated in 4 other conditions, according to our data. His top areas of expertise are Autism Spectrum Disorder, Developmental Expressive Language Disorder, Asperger's Syndrome, Cerebral Palsy, and Heart Transplant.
Antonio Hardan is a Psychiatrist in Stanford, California. Hardan has been practicing medicine for over 35 years and is rated as an Elite expert by MediFind in the treatment of Autism Spectrum Disorder. He is also highly rated in 1 other condition, according to our data. His top areas of expertise are Autism Spectrum Disorder, Legius Syndrome, and Attention Deficit Hyperactivity Disorder (ADHD). Hardan is currently accepting new patients.
Simon Cohen-Baron practices in Cambridge, United Kingdom. Cohen-Baron is rated as an Elite expert by MediFind in the treatment of Autism Spectrum Disorder. He is also highly rated in 2 other conditions, according to our data. His top areas of expertise are Autism Spectrum Disorder, Asperger's Syndrome, Agnosia, and Anorexia.
Many organizations provide additional information and help on ASD.
With the right treatment, many ASD symptoms can be improved. Most people with ASD have some symptoms throughout their lives. But, they're able to live with their families or in the community.
ASD can be linked with other brain disorders, such as:
Some people with autism develop seizures.
The stress of dealing with autism can lead to social and emotional problems for families and caregivers, and for the person with autism.
Parents usually suspect that there is a developmental problem long before a diagnosis is made. Call your provider if you think that your child is not developing normally.
Summary: This research project will investigate if a supplement containing a unique combination of prebiotics and probiotics can influence behaviour in children diagnosed with autism spectrum disorder. The study will use a combination of human milk oligosaccharides (HMOs, prebiotics) and probiotics as an oral powder.This clinical trial will have two consecutive phases. Phase 1A is an 8-week randomised, dou...
Summary: Genetic analyses conducted on patient with psychiatric disorders assessed at the expert centres resulted in the identific action of genetic variants associated with psychiatric disorders (Courtois, 2020). These data require further genetic and functional analyses. The first objective of this study is to investigate the disease-related inheritance of genetic variants in the families of individuals ...
Published Date: June 07, 2022
Published By: Neil K. Kaneshiro, MD, MHA, Clinical Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Bridgemohan CF. Autism spectrum disorder. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 54.
Centers for Disease Control and Prevention website. Autism spectrum disorder (ASD): recommendations and guidelines. www.cdc.gov/ncbddd/autism/hcp-recommendations.html. Updated April 7, 2022. Accessed July 18, 2022.
National Institute of Mental Health website. Autism spectrum disorder. www.nimh.nih.gov/health/topics/autism-spectrum-disorders-asd. Updated March 2022. Accessed July 18, 2022.
Sidhu R, O'Banion DD, Hall C. Autism and other developmental disabilities. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 90.