Autism Spectrum Disorder Clinical Trials

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SIRCUS : Social Information pRocessing in Children:an ocUlo-pupillometric Tool for Standard Evaluation

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this observational study is to identify behavioral and physiological markers of social alterations in Autism Spectrum Disorders compared to Typically Developping peers. This single-centre study plan to use eye tracking to evaluate social disorders in Autism Spectrum Disorders (ASD). The investigators will estimate oculometric and pupillometric indices as potential ASD biomarkers. The study will last 4 years and will be organized in two phases.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 day
Maximum Age: 50
Healthy Volunteers: t
View:

⁃ Phase 1

⁃ All groups have these 2 criteria in common:

⁃ Free, informed and signed consent of both parents Enrolment in the social security system

⁃ The other criteria per group are as follows:

⁃ Group of adult subjects without ASD : Age between 18 and 50 years Group of children without ASD

• Age between 2 and 12 years

• Group of children with ASD Age between 2 and 12 years Conformity with the diagnostic criteria of ASD according to DSM-V, ICD-10 or ICD-11

⁃ Phase 2

• Group of children without TND : Age between 0 and 12 years

• Group of children with TND, or whose diagnosis is in progress (via PCO referral) :

⁃ Age between 0 and 12 years Conformity to the diagnostic criteria of TND

Locations
Other Locations
France
Service de Pédopsychiatrie-CHU-TOURS
RECRUITING
Tours
Contact Information
Primary
Nadia Aguillon-Hernandez, MCU
nadia.aguillon@univ-tours.fr
0247478840
Backup
Yosra DRIDI
Y.ABDERRAHMEN@chu-tours.fr
+33247479792
Time Frame
Start Date: 2023-01-03
Estimated Completion Date: 2026-09
Participants
Target number of participants: 460
Treatments
Other: Group of adult subjects without ASD (Autism Spectrum Disorders)
Age between 18 and 50 years
Other: Group of children without ASD
Age between 2 and 12 years
Other: Group of children with ASD
Age between 2 and 12 years Conformity with the diagnostic criteria of ASD according to DSM-V, ICD-10 or ICD-11
Other: Group of children without NDD (NeuroDevelopmental Disorders)
Age between 0 and 12 years
Other: Group of children with NDD, or whose diagnosis is in progress
Conformity to the diagnostic criteria of NDD
Related Therapeutic Areas
Sponsors
Collaborators: National Research Agency, France, UMR 1253, iBrain, Université de Tours, Inserm, Tours, France., Ministry of Health, France, Laboratory of Fundamental and Applied Computer Science of Tours, EA6300
Leads: University Hospital, Tours

This content was sourced from clinicaltrials.gov

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