Washed Microbiota Transplantation (WMT) for Autism Spectrum Disorder (ASD)

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. A significant comorbidity exists between ADHD and ASD: 30%-50% of individuals with ASD exhibit ADHD symptoms, and two-thirds with ADHD show ASD traits. Intestinal microbial disturbance is common in children with ASD. A great deal of evidence shows that intestinal microbes can influence the brain to play its role through gut-brain-microbiota axis. We intend to explore the role of Washed Microbiota Transplantation in improving symptoms of children in ASD with or without ADHD; To study the potential etiological mechanism of WMT for the neurodevelopmental disorders.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Maximum Age: 17
Healthy Volunteers: f
View:

• Children and adolescents with an established diagnosis of ADHD or ADHD + ASD according to the Diagnostic and Statistical Manual Of Mental Disorders Fifth Edition;.

• Age 3-17 years.

• Received stable treatments for ≥1 month preceding WMT

Locations
Other Locations
China
Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
RECRUITING
Nanjing
SIR RUN RUN hospital of Nanjing Medical University
RECRUITING
Nanjing
Contact Information
Primary
Faming Zhang, PhD
fzhang@njmu.edu.cn
086-25-58509883
Time Frame
Start Date: 2023-09-20
Estimated Completion Date: 2027-05-01
Participants
Target number of participants: 80
Treatments
Experimental: Washed microbiota transplantation
WMT
Related Therapeutic Areas
Sponsors
Leads: The Second Hospital of Nanjing Medical University
Collaborators: Nanjing Medical University

This content was sourced from clinicaltrials.gov