Autism Spectrum Disorder Clinical Trials

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Randomized Controlled Trial of an Online Pivotal Response Treatment Training in Autism Spectrum Disorder

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This is a research study that will assess the effects of a Pivotal Response Treatment Online Training Course (PRT-O) for training parents of children with Autism Spectrum Disorder (ASD). The study will specifically investigate whether participants can learn to deliver PRT effectively following participation in the Online training.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 5
Healthy Volunteers: t
View:

• 2:0 to 5:11 years at the time of consent,

• diagnosed with ASD (based on history, review of available medical records including diagnostic testing, e.g., Autism Diagnostic Observation Schedule) or suspicion of Autism Spectrum Disorder diagnosis, and confirmed with Autism Diagnostic Interview-Revised (ADI-R),

• with significant adaptive communication deficits (i.e., either a Vineland-3 Communication subscale 2 Standard Deviations below average for 2 and 3 year olds and 3 Standard Deviations below for 4 and 5 year olds or a Vineland-3 Expressive V-scale Score 2 Standard Deviations below average for 2 and 3 year olds, or 3 Standard Deviations below for 4 and 5 year old, and at least moderate severity on the Clinical Global Impressions Severity (CGI-S) language subscale),

• an English-speaking parent able to consistently participate in study procedures and conduct treatment in English,

• stable psychotropic medication(s) or biomedical intervention(s) for at least 1 month prior to baseline measurements with no anticipated changes during study participation,

• stable treatment (ABA, Floortime, or other interventions), speech therapy, and school placement for at least 1 month prior to baseline measurements with no expected changes during study participation,

• no more than 60 minutes of 1:1 speech therapy per week

Locations
United States
California
Stanford University
RECRUITING
Stanford
Contact Information
Primary
Estefania Millan, MA
autismdd@stanford.edu
(650) 736-1235
Time Frame
Start Date: 2026-01-30
Estimated Completion Date: 2028-12-30
Participants
Target number of participants: 44
Treatments
Experimental: Pivotal Response Treatment Online (PRT-O) Course
The PRT-O Online Course (PRT-O) will consist of 10 online lessons completed asynchronously through the Stanford LearnMed Online CANVAS Platform. Parents are expected to view the 10 lessons over the course of a 12-week study period, complete worksheets, and to practice PRT at home.
No_intervention: Delayed Treatment Group (DTG)
No intervention.
Related Therapeutic Areas
Sponsors
Leads: Stanford University

This content was sourced from clinicaltrials.gov