Personalized, Responsive Intervention Sequences for Minimally Verbal Children With Autism
This research study, Personalized, Responsive Intervention Sequences for Minimally Verbal Children with Autism (PRISM), is designed to maximize language outcomes for limited-language preschoolers, thereby lowering the risk of being classified as minimally verbal at age 6, by empirically developing a two-stage, 20-week adaptive intervention approach in a real world community settings. If found efficacious, the adaptive intervention design will capitalize on the heterogeneity and evolving status of children with ASD by providing the best intervention (DTT, JASPER and CET) for children who need it (leading to individualized sequences of intervention), only when it is needed (potentially reducing burden on children).
• children meeting ADOS-2 criteria for ASD,
• age 36-59 months
• who have had \> 3 months early intervention/preschool (to ensure that children already have been exposed to some community interventions) and
• use \< 20 functional words (i.e., non-echoed, non-scripted).
⁃ Additional inclusion criteria are:
• stable medication over the past 6 months, and
• nonverbal mental age of \>12 months on the Mullen Scales of Early Learning (visual reception and fine motor subscales).