Autoimmune Polyglandular Syndrome Type 2 Symptoms, Doctors, Treatments, Advances & More

Learn About Autoimmune Polyglandular Syndrome Type 2

What is the definition of Autoimmune Polyglandular Syndrome Type 2?

Autoimmune polyglandular syndrome type 2 is an autoimmune disorder that affects many hormone-producing (endocrine) glands. It is characterized by the presence of Addison's disease along with autoimmune thyroid disease and/or type 1 diabetes. Affected individuals may also have problems with other endocrine glands and other common features include primary hypogonadism, myasthenia gravis, and celiac disease. Autoimmune polyglandular syndrome type 2 is diagnosed in adulthood. The cause of Autoimmune polyglandular syndrome type 2 is unknown, although it may involve a combination of genetic and environmental factors. This condition occurs more often in women than men. Currently, there are no unique tests to detect APS-2, but testing for autoantibodies may be helpful in assessing disease risk, since the relevant autoantibodies (such as antibodies to thyroid peroxidase in autoimmune thyroid disease, or to glutamic acid decarboxylase in type 1 diabetes) are frequently detectable years before disease onset.

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What are the alternative names for Autoimmune Polyglandular Syndrome Type 2?

Autoimmune polyglandular syndrome type 2
APS2
Autoimmune polyendocrine syndrome type 2
Autoimmune polyglandular syndrome type II
Diabetes mellitus, Addison's disease, myxedema
Multiple endocrine deficiency syndrome, type 2
PGA 2
PGA-II
Polyglandular autoimmune syndrome, type 2
Polyglandular deficiency syndrome type 2
Schmidt syndrome
Schmidt's syndrome

Who are the top Autoimmune Polyglandular Syndrome Type 2 Local Doctors?

Part G. Peterson

Elite

Highly rated in

conditions

University Of Tartu

Institute Of Biomedicine And Translational Medicine,

Tartu, EE

Part Peterson practices in Tartu, Estonia. Peterson is rated as an Elite expert by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. They are also highly rated in 9 other conditions, according to our data. Their top areas of expertise are Autoimmune Polyglandular Syndrome Type 2, Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED), Pyle Disease, Familial Chronic Mucocutaneous Candidiasis, and Kidney Transplant.

Saila M. Laakso

Elite

Highly rated in

conditions

Helsinki University Hospital, New Children's Hospital And Jorvi Hospital

Helsinki, FI

Saila Laakso practices in Helsinki, Finland. Laakso is rated as an Elite expert by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. She is also highly rated in 7 other conditions, according to our data. Her top areas of expertise are Autoimmune Polyglandular Syndrome Type 2, Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED), Acute Adrenal Crisis, and Pyle Disease.

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Kai E. Kisand

Elite

Highly rated in

conditions

University Of Tartu

Institute Of Biomedicine And Translational Medicine,

Tartu, EE

Kai Kisand practices in Tartu, Estonia. Kisand is rated as an Elite expert by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. They are also highly rated in 8 other conditions, according to our data. Their top areas of expertise are Autoimmune Polyglandular Syndrome Type 2, Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED), Pyle Disease, and Type 1 Diabetes (T1D).

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What are the latest Autoimmune Polyglandular Syndrome Type 2 Clinical Trials?

A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Enrollment Status: Recruiting

Publish Date: December 15, 2022

Intervention Type: Drug

Study Phase: Phase 2

Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune system makes a mistake and attacks the body. Some people with APECED have a type of hair loss called alopecia areata (AA). No drugs are approved to treat AA.

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Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan

Enrollment Status: Recruiting

Publish Date: October 13, 2022

Intervention Type: Other

Summary: Autoimmune polyendocrine syndrome (APS) is an autoimmune disease involving at least two endocrine organ. It is classified into type I and type II diseases. Among them, APS type II is more common. It is diagnosed when two of the three following diseases are diagnosed in the same patient, including type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency. In this study...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Autoimmune Polyglandular Syndrome Type 2?