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Learn About Autoimmune Polyglandular Syndrome Type 2

What is the definition of Autoimmune Polyglandular Syndrome Type 2?
Autoimmune polyglandular syndrome type 2 is an autoimmune disorder that affects many hormone-producing (endocrine) glands. It is characterized by the presence of Addison's disease along with autoimmune thyroid disease and/or type 1 diabetes. Affected individuals may also have problems with other endocrine glands and other common features include primary hypogonadism, myasthenia gravis, and celiac disease. Autoimmune polyglandular syndrome type 2 is diagnosed in adulthood. The cause of Autoimmune polyglandular syndrome type 2 is unknown, although it may involve a combination of genetic and environmental factors. This condition occurs more often in women than men. Currently, there are no unique tests to detect APS-2, but testing for autoantibodies may be helpful in assessing disease risk, since the relevant autoantibodies (such as antibodies to thyroid peroxidase in autoimmune thyroid disease, or to glutamic acid decarboxylase in type 1 diabetes) are frequently detectable years before disease onset.
What are the alternative names for Autoimmune Polyglandular Syndrome Type 2?
  • Autoimmune polyglandular syndrome type 2
  • APS2
  • Autoimmune polyendocrine syndrome type 2
  • Autoimmune polyglandular syndrome type II
  • Diabetes mellitus, Addison's disease, myxedema
  • Multiple endocrine deficiency syndrome, type 2
  • PGA 2
  • PGA-II
  • Polyglandular autoimmune syndrome, type 2
  • Polyglandular deficiency syndrome type 2
  • Schmidt syndrome
  • Schmidt's syndrome
Who are the top Autoimmune Polyglandular Syndrome Type 2 Local Doctors?
Pediatrics | Internal Medicine
Pediatrics | Internal Medicine

Mainehealth

5 Bucknam Rd, 
Falmouth, ME 
 10.7 mi
Accepting New Patients
Offers Telehealth

Ryan Close is a Pediatrics specialist and an Internal Medicine provider in Falmouth, Maine. Dr. Close and is rated as an Experienced provider by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. His top areas of expertise are COVID-19, Streptococcal Group A Infection, Childhood Iron Deficiency Anemia, and Maturity Onset Diabetes of the Young. Dr. Close is currently accepting new patients.

Richard J. Comi
Endocrinology
Endocrinology

Dartmouth-Hitchcock Clinic

1 Medical Ctr Dr, 
Lebanon, NH 
 97.1 mi
Offers Telehealth

Richard Comi is an Endocrinologist in Lebanon, New Hampshire. Dr. Comi and is rated as an Advanced provider by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. His top areas of expertise are Type 1 Diabetes (T1D), Type 2 Diabetes (T2D), Hypothyroidism, and Pituitary Tumor.

 
 
 
 
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Endocrinology
Endocrinology
480 Maple St, 
Danvers, MA 
 76.6 mi
Offers Telehealth

Michael Gordon is an Endocrinologist in Danvers, Massachusetts. Dr. Gordon has been practicing medicine for over 43 years and is rated as an Advanced provider by MediFind in the treatment of Autoimmune Polyglandular Syndrome Type 2. His top areas of expertise are Obesity in Children, Hashimoto Thyroiditis, Type 2 Diabetes (T2D), and Hyperparathyroidism.

What are the latest Autoimmune Polyglandular Syndrome Type 2 Clinical Trials?
A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune system makes a mistake and attacks the body. Some people with APECED have a type of hair loss called alopecia areata (AA). No drugs are approved to treat AA.

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The Natural History and Pathogenesis of Human Fungal Infections

Background: - The immune system is made up of special cells, tissues, and organs that fight infections. Problems with this system may lead to frequent, severe, or unusual fungal infections. These infections are often difficult to treat. Researchers want to collect blood and tissue samples from people who have unusual, persistent or severe fungal infections or immune problems that increase the risk of these in...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center