Learn About Autosomal Recessive Hypotrichosis

What is the definition of Autosomal Recessive Hypotrichosis?

Autosomal recessive hypotrichosis is a condition that affects hair growth. People with this condition have sparse hair (hypotrichosis) on the scalp beginning in infancy. This hair is usually coarse, dry, and tightly curled (often described as woolly hair). Scalp hair may also be lighter in color than expected and is fragile and easily broken. Affected individuals often cannot grow hair longer than a few inches. The eyebrows, eyelashes, and other body hair may be sparse as well. Over time, the hair problems can remain stable or progress to complete scalp hair loss (alopecia) and a decrease in body hair.

Save information for later
Sign Up
What are the causes of Autosomal Recessive Hypotrichosis?

Autosomal recessive hypotrichosis can be caused by mutations in the LIPH, LPAR6, or DSG4 gene. These genes provide instructions for making proteins that are involved in the growth and division (proliferation) and maturation (differentiation) of cells within hair follicles. These cell processes are important for the normal development of hair follicles and for hair growth; as the cells in the hair follicle divide, the hair strand (shaft) is pushed upward and extends beyond the skin, causing the hair to grow. The proteins produced from the LIPH, LPAR6, and DSG4 genes are also found in the outermost layer of skin (the epidermis) and glands in the skin that produce a substance that protects the skin and hair (sebaceous glands).

How prevalent is Autosomal Recessive Hypotrichosis?

The worldwide prevalence of autosomal recessive hypotrichosis is unknown. In Japan, the condition is estimated to affect 1 in 10,000 individuals.

Is Autosomal Recessive Hypotrichosis an inherited disorder?

This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

Who are the top Autosomal Recessive Hypotrichosis Local Doctors?
Elite
Highly rated in
36
conditions
Dermatology

Atrium Health Wake Forest Baptist

Wake Forest University Health Sciences

4618 Country Club Rd 
Winston Salem, NC 27104

Amy Mcmichael is a Dermatologist in Winston Salem, North Carolina. Dr. Mcmichael has been practicing medicine for over 32 years and is rated as an Elite doctor by MediFind in the treatment of Autosomal Recessive Hypotrichosis. She is also highly rated in 36 other conditions, according to our data. Her top areas of expertise are Autosomal Recessive Hypotrichosis, Alopecia Areata, Female Pattern Baldness, and Male Pattern Baldness. She is licensed to treat patients in North Carolina. Dr. Mcmichael is currently accepting new patients.

Elite
Highly rated in
12
conditions
Dermatology

M Health Fairview

University Of Minnesota Physicians

909 Fulton St Se 
Minneapolis, MN 55455

Maria Hordinsky is a Dermatologist in Minneapolis, Minnesota. Dr. Hordinsky has been practicing medicine for over 46 years and is rated as an Elite doctor by MediFind in the treatment of Autosomal Recessive Hypotrichosis. She is also highly rated in 12 other conditions, according to our data. Her top areas of expertise are Alopecia Areata, Autosomal Recessive Hypotrichosis, Female Pattern Baldness, and Graham-Little-Piccardi-Lassueur Syndrome. She is licensed to treat patients in Minnesota. Dr. Hordinsky is currently accepting new patients.

 
 
 
 
Learn about our expert tiers
Learn more
Elite
Highly rated in
39
conditions
Dermatology

Memorial Sloan Kettering Cancer Center

1275 York Ave 
New York, NY 10065

Mario Lacouture is a Dermatologist in New York, New York. Dr. Lacouture has been practicing medicine for over 15 years and is rated as an Elite doctor by MediFind in the treatment of Autosomal Recessive Hypotrichosis. He is also highly rated in 39 other conditions, according to our data. His top areas of expertise are Autosomal Recessive Hypotrichosis, Female Pattern Baldness, Male Pattern Baldness, and Hartsfield Syndrome. He is licensed to treat patients in Illinois and New York. Dr. Lacouture is currently accepting new patients.

What are the latest Autosomal Recessive Hypotrichosis Clinical Trials?
Pilot Exploratory Study to Determine Effect of Gentle Wounding to Stimulate Hair Follicle Neogenesis
Match to trials
Find the right clinical trials for you in under a minute
Get started
The Epidemiology, Management, and the Associated Burden of Mental Health, Atopic and Autoimmune Conditions, and Common Infections in Alopecia Areata
Who are the sources who wrote this article ?

Published Date:updated Last, April

Published By: National Institutes of Health

What are the Latest Advances for Autosomal Recessive Hypotrichosis?
Unilateral branch retinal artery occlusion in a patient with systemic lupus erythematosus: A case report.
Two Phase 3 Trials of Baricitinib for Alopecia Areata.
Tired of the same old research?
Check Latest Advances
Platelet Rich Plasma for the Treatment of Scarring Alopecia Due to Discoid Lupus Erythematosus.