B-Cell Lymphoma Overview

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Learn About B-Cell Lymphoma

What is the definition of B-Cell Lymphoma?
B-cell lymphoma refers to types of non-Hodgkin lymphoma that are characterized by abnormalities of the "B-cells" (a type of white blood cell that makes antibodies to help fight infection). The condition may grow and spread slowly with few symptoms (also known as indolent lymphoma) or may be very aggressive with severe symptoms. When present, signs and symptoms may include swollen lymph nodes in the neck, armpit, or groin; abdominal pain; fatigue; fever; night sweats; and/or weight loss. The underlying cause of B-cell lymphoma is poorly understood. However, the condition can be associated with genetic abnormalities, environmental factors, viruses, immunodeficiency states, and connective-tissue disorders.
What are the alternative names for B-Cell Lymphoma?
  • B-cell lymphoma
  • Lymphoma, B-Cell
Who are the top B-Cell Lymphoma Local Doctors?
Alex F. Herrera
Elite in B-Cell Lymphoma
Dr. Alex F. Herrera
Hematology | Hematology Oncology
Elite in B-Cell Lymphoma
Dr. Alex F. Herrera
Hematology | Hematology Oncology

City Of Hope - Duarte Main Campus

1500 E Duarte Rd, 
Duarte, CA 
626-256-4673
Experience:
16+ years
Languages Spoken:
English
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Offers Telehealth

Alex Herrera is a Hematologist and a Hematologist Oncology provider in Duarte, CA. Dr. Herrera has been practicing medicine for over 16 years and is rated as an Elite provider by MediFind in the treatment of B-Cell Lymphoma. His top areas of expertise are Hodgkin Lymphoma, Classical Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma (DLBCL), Bone Marrow Transplant, and Bone Marrow Aspiration.

Elite in B-Cell Lymphoma
Dr. Sattva S. Neelapu
Oncology | Hematology
Elite in B-Cell Lymphoma
Dr. Sattva S. Neelapu
Oncology | Hematology

MD Anderson

2130 W Holcombe Blvd, Univ Of Tx M D Ande Life, 
Houston, TX 
713-592-5433
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Sattva Neelapu is an Oncologist and a Hematologist in Houston, Texas. Dr. Neelapu is rated as an Elite provider by MediFind in the treatment of B-Cell Lymphoma. His top areas of expertise are Non-Hodgkin Lymphoma, Follicular Lymphoma, B-Cell Lymphoma, Tissue Biopsy, and Bone Marrow Transplant.

 
 
 
 
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Elite in B-Cell Lymphoma
Dr. Christopher R. Flowers
Hematology Oncology | Transplant Surgery | Oncology
Elite in B-Cell Lymphoma
Dr. Christopher R. Flowers
Hematology Oncology | Transplant Surgery | Oncology

MD Anderson

1515 Holcombe Blvd, 
Houston, TX 
713-792-2121
Languages Spoken:
English
See accepted insurances

Christopher Flowers is a Hematologist Oncology specialist and a Transplant Surgeon in Houston, Texas. Dr. Flowers is rated as an Elite provider by MediFind in the treatment of B-Cell Lymphoma. His top areas of expertise are Non-Hodgkin Lymphoma, Follicular Lymphoma, B-Cell Lymphoma, Bone Marrow Transplant, and Tissue Biopsy.

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What are the latest B-Cell Lymphoma Clinical Trials?
A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of AZD0486, a Bispecific Antibody Targeting CD19 in Subjects With B-Cell Non-Hodgkin Lymphoma
A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of AZD0486, a Bispecific Antibody Targeting CD19 in Subjects With B-Cell Non-Hodgkin Lymphoma
Who is this study for: Adult patients with relapsed or refractory b-cell non-Hodgkin's lymphoma
Enrollment Status: Recruiting
Publish Date: October 15, 2025
Intervention Type: Drug
Study Drug: TNB-486
Study Phase: Phase 1

Summary: This phase 1 study will investigate the safety, tolerability, pharmacokinetic, pharmacodynamic, and clinical activity of AZD0486, a CD19 x CD3 T-cell engaging bispecific antibody, in subjects with B-cell non-Hodgkin lymphoma (B-NHL).

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A Phase 2 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed or Refractory CD10-Negative Diffuse-Large B-Cell Lymphoma (DLBCL) and High-Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements (HGBCL-DH-BCL2)
A Phase 2 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed or Refractory CD10-Negative Diffuse-Large B-Cell Lymphoma (DLBCL) and High-Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements (HGBCL-DH-BCL2)
Enrollment Status: Recruiting
Publish Date: October 15, 2025
Intervention Type: Procedure, Drug, Biological
Study Phase: Phase 2

Summary: This phase II trial tests how well venetoclax, ibrutinib, prednisone, obinutuzumab, and Revlimid® (ViPOR) works in treating patients with CD10 negative diffuse large B-cell lymphoma (DLBCL) and high-grade lymphoma with MYC and BCL2 rearrangements that has come back after a period of improvement (relapsed) and/or that has not responded to previous treatment (refractory). Venetoclax is in a class of...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center