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Glofitamab in Real Life

Status: Recruiting
Location: See all (30) locations...
Intervention Type: Drug
Study Type: Observational
SUMMARY

To date, more than 300 patients have been treated with Glofitamab in the Expanded Access Programme (EAP) in France. In this study, it is proposed to perform a retrospective analysis of some of these patients. The aim is to describe the efficacy and safety of Glofitamab in the largest reported real-world cohort, with an expected median follow-up of more than 9 months. Particular focus will be given to the relapsed or refractory chimeric antigen receptors-T (CAR-T) population to confirm the response rates (CRR: 35-39%) of Glofitamab in this population and to assess the optimal timing of therapy initiation \[8, 15\].

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• patient enrolled in the French Glofitamab EAP for R/R DLBCL before 2024 November 1st, 2024

• patient who received at least Obinutuzumab pretreatment and one infusion of Glofitamab

• adult patient

• patient who is informed of the study and who did not oppose to their data collection

Locations
Other Locations
France
CH Victor Dupouy
RECRUITING
Argenteuil
CH d'Avignon - Hôpital Henri Dufaut
RECRUITING
Avignon
CH de la Côte Basque
RECRUITING
Bayonne
CHRU Besançon - Hôpital Minjoz
RECRUITING
Besançon
Hopital D'Instruction Des Armees Percy
RECRUITING
Clamart
Hopital Henri Mondor
RECRUITING
Créteil
CHU de Dijon - Hôpital le Bocage
RECRUITING
Dijon
CH de Dunkerque
RECRUITING
Dunkirk
CHU de Grenoble - Hôpital Albert Michallon
RECRUITING
La Tronche
Hôpital de Libourne
RECRUITING
Libourne
CHRU de LILLE - Claude Huriez
RECRUITING
Lille
Hopital Saint Vincent-de-Paul
RECRUITING
Lille
Centre Léon Bérard
RECRUITING
Lyon
INSTITUT PAOLI CALMETTES - Service Hématologie
RECRUITING
Marseille
Clinique du Pont de Chaume
RECRUITING
Montauban
CH de Mulhouse Sud Alsace
RECRUITING
Mulhouse
CHR d'Orléans
RECRUITING
Orléans
Hopital Saint-Louis
RECRUITING
Paris
Chu de Bordeaux - Hopital Haut-Leveque
RECRUITING
Pessac
CHU Lyon Sud
RECRUITING
Pierre-bénite
CHU de Poitiers - Hôpital de La Milétrie
RECRUITING
Poitiers
CH de Quimper Cornouaille
RECRUITING
Quimper
CHU de Rennes - Hôpital de Pontchaillou
RECRUITING
Rennes
Institut Curie - Site Saint-Cloud
RECRUITING
Saint-cloud
CHU de Strasbourg
RECRUITING
Strasbourg
Institut Universitaire du Cancer de Toulouse - Oncopole
RECRUITING
Toulouse
Chu Bretonneau
RECRUITING
Tours
CHRU de Nancy - Hôpital de Brabois
RECRUITING
Vandœuvre-lès-nancy
Ch de Bretagne Atlantique
RECRUITING
Vannes
Gustave Roussy Cancer Campus Grand Paris
RECRUITING
Villejuif
Contact Information
Primary
PROJECT MANAGER
glorel@lysarc.org
+33 4 72 66 93 33
Time Frame
Start Date: 2025-12-01
Estimated Completion Date: 2026-12-30
Participants
Target number of participants: 250
Treatments
Patients treated in EPA
Patients treated in Expanded Access Program to Glofitamab
Related Therapeutic Areas
Sponsors
Leads: The Lymphoma Academic Research Organisation

This content was sourced from clinicaltrials.gov

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