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Learn About Bare Lymphocyte Syndrome

What is the definition of Bare Lymphocyte Syndrome?
A rare autosomal recessive primary immunodeficiency characterized by severe reduction in the cell surface expression of HLA class I molecules, typically resulting in childhood-onset of chronic bacterial infections of the respiratory tract evolving to widespread bronchiectasis and respiratory insufficiency. Sterile necrotizing granulomatous skin lesions mainly involving the extremities and the mid-face may be observed in some patients. Severe viral infections do not occur as part of the condition. Atypical variants without respiratory or cutaneous manifestations, as well as asymptomatic individuals have been reported.
What are the alternative names for Bare Lymphocyte Syndrome?
  • Bare lymphocyte syndrome
  • BLS type 1
  • HLA class 1 deficiency
Who are the top Bare Lymphocyte Syndrome Local Doctors?
Distinguished in Bare Lymphocyte Syndrome
Distinguished in Bare Lymphocyte Syndrome

Erasmus MC

Rotterdam, ZH, NL 

Mirjam Van Der Burg-Van Der Borght practices in Rotterdam, Netherlands. Van Der Burg-Van Der Borght is rated as a Distinguished expert by MediFind in the treatment of Bare Lymphocyte Syndrome. Their top areas of expertise are Severe Combined Immunodeficiency (SCID), Common Variable Immune Deficiency, Bare Lymphocyte Syndrome, Bone Marrow Transplant, and Thymectomy.

Advanced in Bare Lymphocyte Syndrome
General Surgery
Advanced in Bare Lymphocyte Syndrome
General Surgery

Hackensack University Medical Center

30 Prospect Avenue, Pediatric Surgery, Wfan, Pc 311, 
Hackensack, NJ 
Languages Spoken:
English

Jason Fisher is a General Surgeon in Hackensack, New Jersey. Dr. Fisher is rated as an Advanced provider by MediFind in the treatment of Bare Lymphocyte Syndrome. His top areas of expertise are Antigen-Peptide-Transporter 2 Deficiency, Bare Lymphocyte Syndrome, Imperforate Anus, Appendectomy, and Oophorectomy.

 
 
 
 
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Kenneth R. Cooke
Experienced in Bare Lymphocyte Syndrome
Experienced in Bare Lymphocyte Syndrome

Johns Hopkins Children's Center

1800 Orleans Street, Bloomberg 11N, Bloomberg 11N, 
Baltimore, MD 
Languages Spoken:
English

Dr. Cooke is Director of the Johns Hopkins Kimmel Cancer Center’s Pediatric Bone Marrow Transplantation Program. Prior to his appointment at Johns Hopkins, Dr. Cooke headed the Pediatric Blood and Marrow Transplantation Program at Rainbow Babies and Children’s Hospital, and University Hospitals Case Medical Center, in Cleveland, Ohio. He also co-directed the Hematologic Disorders Program of the Case Comprehensive Cancer Center at Case Western Reserve University. A nationally recognized transplantation immunology expert, Dr. Cooke focuses primarily on new strategies to prevent and treat graft-vs-host disease and lung complications following blood and bone marrow transplantation. His research efforts have been recognized by the Leukemia and Lymphoma Society and the American Society of Clinical Investigation. In addition to his younger patients, Dr. Cooke also cares for adolescents and young adults. Dr. Cooke is rated as an Experienced provider by MediFind in the treatment of Bare Lymphocyte Syndrome. His top areas of expertise are Graft Versus Host Disease (GvHD), Chronic Graft Versus Host Disease (cGvHD), Anemia, Aplastic Anemia, and Bone Marrow Transplant.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center