Behcet Disease Overview
Learn About Behcet Disease
Behçet disease is an inflammatory condition that affects many parts of the body. The health problems associated with Behçet disease result from widespread inflammation of blood vessels (vasculitis). This inflammation most commonly affects small blood vessels in the mouth, genitals, skin, and eyes.
The cause of Behçet disease is unknown. The condition probably results from a combination of genetic and environmental factors, most of which have not been identified. However, a particular variation in the HLA-B gene has been associated with the risk of developing Behçet disease.
Behçet disease is most common in Mediterranean countries, the Middle East, Japan, and other parts of Asia. However, it has been found in populations worldwide.
Most cases of Behçet disease are sporadic, which means they occur in people with no history of the disorder in their family. A small percentage of all cases have been reported to run in families; however, the condition does not have a clear pattern of inheritance.
University Of Penn - Medical Group
Peter Merkel is a Rheumatologist in Philadelphia, Pennsylvania. Dr. Merkel and is rated as an Advanced provider by MediFind in the treatment of Behcet Disease. His top areas of expertise are Granulomatosis with Polyangiitis, Vasculitis, Microscopic Polyangiitis, Takayasu Arteritis, and Tissue Biopsy.
University Of Penn - Medical Group
Preethi Thomas is a Rheumatologist in Philadelphia, Pennsylvania. Dr. Thomas and is rated as an Advanced provider by MediFind in the treatment of Behcet Disease. Her top areas of expertise are Dermatomyositis, Polymyositis, Rheumatoid Arthritis (RA), and Systemic Lupus Erythematosus (SLE).
University Of Penn - Medical Group
Shubhasree Banerjee is a Rheumatologist in Philadelphia, Pennsylvania. Dr. Banerjee and is rated as an Advanced provider by MediFind in the treatment of Behcet Disease. Her top areas of expertise are Relapsing Polychondritis, Temporal Arteritis, Giant Cell Arteritis (GCA), and Juvenile Temporal Arteritis.
Summary: The objective of this study is to evaluate the efficacy and safety of BCMA/CD19 chimeric antigen receptor (CAR)-modified T cells in the treatment of autoimmune diseases.
Summary: The study is to evaluate the efficacy and safety of lenalidomide in the treatment of oral ulcers in adult patients with refractory mucosal Behcet's syndrome.
Published Date: June 01, 2017
Published By: National Institutes of Health