Learn About Bile Duct Stricture

What is the definition of Bile Duct Stricture?

A bile duct stricture is an abnormal narrowing, most often of the common bile duct. This is a tube that moves bile from the liver to the small intestine. Bile is a substance that helps with digestion.

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What are the alternative names for Bile Duct Stricture?

Bile duct stricture; Biliary stricture

What are the causes of Bile Duct Stricture?

A bile duct stricture is often caused by injury to the bile ducts during surgery. For example, it may occur after surgery to remove the gallbladder.

Other causes of this condition include:

  • Cancer of the bile duct, liver or pancreas
  • Damage and scarring due to a gallstone in the bile duct
  • Damage or scarring after gallbladder removal
  • Pancreatitis
  • Primary sclerosing cholangitis
What are the symptoms of Bile Duct Stricture?

Symptoms include:

  • Abdominal pain on the upper right side of belly
  • Chills
  • Fever
  • Itching
  • General feeling of discomfort
  • Loss of appetite
  • Jaundice
  • Nausea and vomiting
  • Pale or clay-colored stools
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What are the current treatments for Bile Duct Stricture?

The goal of treatment is to correct the narrowing. This will allow bile to flow from the liver into the intestine.

This may involve:

  • Surgery
  • Endoscopic or percutaneous dilation or insertion of stents through the stricture

If surgery is done, the stricture is removed. The common bile duct will be rejoined with the small intestine.

In some cases, a tiny metal or plastic mesh tube (stent) is placed across the bile duct stricture to keep it open.

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What is the outlook (prognosis) for Bile Duct Stricture?

Treatment is successful most of the time. Long-term success depends on the cause of the stricture.

What are the possible complications of Bile Duct Stricture?

Inflammation and narrowing of the biliary duct may return in some people. There is a risk for infection above the narrowed area. Strictures that remain for a long period can lead to liver damage (cirrhosis).

When should I contact a medical professional for Bile Duct Stricture?

Contact your health care provider if symptoms recur after pancreatitis, cholecystectomy, or other biliary surgery.

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What are the latest Bile Duct Stricture Clinical Trials?
Role of Biodegradable Polydioxanone Biliary Stents for the Percutaneous Treatment of Benign Biliary Strictures.

Summary: To assess safety and effectiveness in the long term of percutaneous insertion of Biodegradable (BD) Biliary Stents for the treatment of benign biliary strictures, in a single center experience.

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Comparison Between Transpapillary and Suprapapillary Metal Stent Placement With Endoscopic Sphincterotomy in Common Bile Duct Malignant Obstruction: Prospective Randomized Controlled Study

Summary: If surgical treatment is not possible in patients with malignant obstruction in the common bile duct, placing metal stents using endoscopy is a standardized treatment to resolve biliary obstruction. The metal stent is located in the bile duct to cover the stenotic portion by malignant tumors. The lower end of the metal stent can be located inside the common bile duct above the major ampulla or in ...

Who are the sources who wrote this article ?

Published Date: May 04, 2022
Published By: Michael M. Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Dudeja V, Ferrantella A, Fong Y. The liver. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. St Louis, MO: Elsevier; 2022:chap 54.

Fogel EL, Sherman S. Diseases of the gallbladder and bile ducts. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 146.

Ibrahim-zada I, Ahrendt SA. Management of benign biliary strictures. In: Cameron AM, Cameron JL, eds. Current Surgical Therapy. 13th ed. Philadelphia, PA: Elsevier; 2020:462-466.

Williams MJ, Gordon-Walker TT. Hepatology. In: Penman ID, Ralston SH, Strachan MWJ, Hobson RP, eds. Davidson's Principles and Practice of Medicine. 24th ed. Philadelphia, PA: Elsevier; 2023:chap 24.