Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY
This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at Vanderbilt. Outcomes will include intra- and post-operative bleeding and postoperative bruising and swelling.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Adults at least 18 years of age who elect to undergo cosmetic or functional open primary rhinoplasty with osteotomies (repositioning the nasal bones) by Drs. Yang or Patel at VUMC.
• No other facial plastics procedure nor sinus surgery performed simultaneously
• Lack all the below Exclusion Criteria
Locations
United States
Tennessee
Vanderbilt University Medical Center
RECRUITING
Nashville
Contact Information
Primary
Shiayin F Yang, MD
jaclyn.lee.1@vumc.org
(615) 322-6180
Backup
Jaclyn Lee, MD
jaclyn.lee.1@vumc.org
(615) 322-6180
Time Frame
Start Date: 2023-04-01
Estimated Completion Date: 2026-02-01
Participants
Target number of participants: 60
Treatments
Experimental: Tranexamic Acid
Patients receive 1 gram IV tranexamic acid in the operating room prior to surgical incision.
No_intervention: Control
Routine care, no tranexamic acid given.
Related Therapeutic Areas
Sponsors
Leads: Vanderbilt University Medical Center