Learn About Bowen's Disease

What is the definition of Bowen's Disease?
A form of squamous cell carcinoma in situ. It is a distinct clinicopathological entity and arises from the skin or the mucocutaneous junction. It affects predominantly white males in their 6-8th decades of life. Exposed and non-exposed skin sites are equally affected. UV damage and ingestion of inorganic arsenic may play a role in the development of the disease. On the skin surface, it presents as a single or multiple erythematous, scaly, keratotic patches or plaques. The clinical entity of erythroplasia of Queyrat is regarded as Bowen disease of the penis and it presents as an asymptomatic, red, circumscribed plaque. Morphologically, Bowen disease is characterized by the presence of hyperkeratosis, parakeratosis, dyskeratosis, and acanthosis. The keratotic squamous cells are atypical and display hyperchromatism and abnormal mitotic figures. The dermoepidermal basement membrane is intact. Complete surgical removal of the lesion may be curative.
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What are the alternative names for Bowen's Disease?
  • Bowen's disease
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What are the latest Bowen's Disease Clinical Trials?
A Multicentre, Prospective, Low-intervention Clinical Trial to Validate a Mobile Application (ProRodinki) in Assessing the Risk of Skin Malignancies

Summary: A Multicenter, Prospective, Low-interventional Clinical Study Evaluating on mobile application validation (ProRodinki) in assessing the risk of skin malignant neoplasms

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Using a Cold Atmospheric Plasma Device to Treat Skin Disorders

Summary: This study examines the efficacy of a non-thermal, atmospheric plasma device in the treatment of skin disorders

Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Bowen's Disease?
Immunocryosurgery is a safe and feasible treatment for basal cell carcinoma and Bowen disease in renal transplant recipients.
Durable Clearance Rate of Photodynamic Therapy for Bowen Disease and Cutaneous Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
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