Cognitive Function and Fatigue After Brain Abscess

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Brain abscess is a focal bacterial or fungal infection of the brain. Treatment is neurosurgical drainage of pus followed by long-term antibiotic treatment. In spite of successful treatment of the infection, long-term cognitive problems or mental fatigue may ensue. The reason for this dysfunction may be a continuing inflammatory state or damage to brain tissue caused by the abscess. The investigators will evaluate these possibilities with the use of \[18F\]deoxyglucose-positron emission tomography (FDG-PET) and electroencephalography (EEG) in patients who have been treated for brain abscess and who experience cognitive problems and/or fatigue. FDG-PET may identify both inflammation and altered neuronal activity (the latter indicating damage to brain tissue), and EEG may identify altered neuronal activity, including changes in neuronal network activity.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: f
View:

• • Patients who have completed treatment for brain abscess and who agree to participate.

Locations
Other Locations
Norway
Oslo University Hospital
RECRUITING
Oslo
Contact Information
Primary
Peder H Utne
pedutn@ous-hf.no
+4723066023
Time Frame
Start Date: 2020-01-01
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 50
Treatments
Brain abscess patients with cognitive dysfunction and/or fatigue
This group of patients experience cognitive dysfunction and/or fatigue after brain abscess.
Brain abscess patients without cognitive dysfunction and/or fatigue
This group of patients does not experience cognitive dysfunction and/or fatigue after brain abscess.
Related Therapeutic Areas
Sponsors
Collaborators: Sunnaas Rehabilitation Hospital, Oslo University Hospital
Leads: University of Oslo

This content was sourced from clinicaltrials.gov