Analysis of the Immunogenetic Profile of Patients With Aggressive Course of Malignant Neoplastic Process Resistant to the Standard Treatment Approaches: a Translational Study
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The investigators will collect biosamples of patient blood and tumour tissue for further immunological analysis of blood cell subpopulations, immunosupressive factors concentration, HLA expression an lymphocytes and tumour tissue, and and cancer testis antigenes expression on tumour cells, as well as clinical data on patient's stage, therapy, response and demographics. Possible prognostic and predictive dynamic biomarkers will be discovered for individualisation of treatment strategies
Eligibility
Participation Requirements
Sex: All
Minimum Age: 1
Healthy Volunteers: f
View:
• Signed inform consent
• Histolgically verified solid tumour
• Receiving systemic therapy for neoplasm
• Has archival tumour tissue
• Provide biosamples with living tumour tissue or blood samples for immunologic assessment
Locations
Other Locations
Russian Federation
N.N. Petrov NMRC of Oncology, Oncoimmunology dep.
RECRUITING
Saint Petersburg
Contact Information
Primary
Aleksei Novik, MD, PhD
alexey.viktorovich.novik@gmail.com
+78124399505
Backup
Tatiana Nekhaeva, MD, PhD
nehaevat151274@mail.ru
+78124399514
Time Frame
Start Date: 1998-09
Estimated Completion Date: 2030-12
Participants
Target number of participants: 1000
Treatments
Melanoma
Soft tissue sarcoma
Kidney cancer
Primary brain tumors
Malignant neoplasms
Prostate cancer
Colorectal cancer
Related Therapeutic Areas
Sponsors
Leads: N.N. Petrov National Medical Research Center of Oncology