High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study (HYPE)

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to determine whether a 16-week virtual, home-based, high-intensity interval training (HIIT) exercise program will improve physical, cognitive, and emotional health among young adult survivors of pediatric brain tumors. The names of the study interventions involved in this study are/is: * High-Intensity Interval Training (HIIT)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 39
Healthy Volunteers: t
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• Written informed consent prior to any study-related procedures.

• At time of study are a young adult, aged 18-39 years.

• Histologically diagnosed brain tumor during childhood (diagnosed ≤18 years).

• Are at least 2 years post tumor-directed therapy.

• The effects of exercise on the developing fetus are unknown. For this reason, women of child-bearing potential must agree to undergo a pregnancy test and to use adequate contraception (hormonal or barrier method of birth control or abstinence) prior to study entry and for six months following duration of study participation. Should a woman become pregnant or suspect that she is pregnant while participating on the trial, she should inform her treating physician immediately.

• Medically cleared to participate in exercise by their referred physician or a certified clinical exercise physiologist.

• Are without medical conditions that could exacerbate with exercise, such as bone disease (excluding bone metastases) at imminent risk of fracture or uncontrolled cardiopulmonary or metabolic diseases.

• Speak English and/or Spanish.

• Currently participate in less than or equal to 60 minutes of moderate or vigorous structured exercise/week.

• Does not smoke or vape (no smoking/vaping during previous 12 months).

• Willing to travel to DFCI for necessary data collection.

• Ability to understand and the willingness to sign a written informed consent document.

Locations
United States
Massachusetts
Dana Farber Cancer Institute
RECRUITING
Boston
Contact Information
Primary
Christina Dieli-Conwright, PhD, MPH
ChristinaM_Dieli-Conwright@dfci.harvard.edu
617-582-8321
Time Frame
Start Date: 2023-12-04
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 30
Treatments
Experimental: HIIT Exercise Program Group
Participants will be randomly assigned to the HIIT exercise group and receive:~* 3x weekly for 16 week home-based virtually supervised High-Intensity Interval Training.~* 16-week self-directed exercise follow up period.~* 3 On-site visits at Week 1, 18 and 34 for assement testing and completion of questionnaires
Active_comparator: Control Group
Participants will be randomly assigned to the HIIT waitlist control group and receive:~* Daily usual activities~* 2 On-site visits at Week 1, and 18 for assement testing and completion of questionnaires~* Option to complete 16 week, 3x weekly HIIT exercise program after initial 16 week period.
Related Therapeutic Areas
Sponsors
Collaborators: Pedals For Pediatrics, The Childhood Brain Tumor Foundation, Stahl Family Charitable Foundation
Leads: Dana-Farber Cancer Institute

This content was sourced from clinicaltrials.gov