Cognitive Training in the Virtual Reality Setting With Children Undergoing Radiotherapy for Brain Tumors

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The objective of this study is to estimate the feasibility and acceptability of cognitive training in the virtual reality setting with children undergoing radiotherapy for brain tumors. To achieve this goal, the investigators plan to study children undergoing radiotherapy for brain tumors randomly assigned to cognitive training administered via an iPad or virtual reality. Both groups will also participate in cognitive testing and exams using functional near infrared spectroscopy (fNIRS) pre- and post-intervention. The questions to be investigated are: 1. Will cognitive training via virtual reality be feasible and acceptable for children undergoing radiotherapy for brain tumors as indicated by participation rates, adherence and frequency of side effects? 2. Will cognitive training via virtual reality provide neurocognitive benefits? 3. Will there be predictable changes in brain activity as measured by neuroimaging? Findings from this study will be used to develop a larger, definitive trial with direct potential to improve cognitive outcomes for children treated for cancer using a safe and effective alternative to desktop- or laptop-based computerized cognitive interventions with great promise for improving quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 8
Maximum Age: 22
Healthy Volunteers: f
View:

• Initiating radiotherapy for a BT

• Between 8-22 years of age at the time of enrollment

• English or Spanish as the primary language

• Research participant and one parent willing to participate and provide consent/assent according to institutional guidelines

• Participant willing to take part in required aspects of Cogmed training

Locations
United States
Tennessee
St. Jude Children's Research Hospital
RECRUITING
Memphis
Contact Information
Primary
Heather Conklin, PhD
referralinfo@stjude.org
901-595-3585
Time Frame
Start Date: 2023-06-22
Estimated Completion Date: 2027-03
Participants
Target number of participants: 45
Treatments
Active_comparator: IPad Cogmed Training
The investigator will be randomizing participants to complete Cogmed training on an iPad.
Experimental: Virtual Reality Cogmed Training
The investigator will be randomizing participants to complete Cogmed training in Virtual Reality.
Related Therapeutic Areas
Sponsors
Leads: St. Jude Children's Research Hospital

This content was sourced from clinicaltrials.gov