Bronchiolitis Obliterans Overview

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Learn About Bronchiolitis Obliterans

What is the definition of Bronchiolitis Obliterans?
Bronchiolitis obliterans is an inflammatory condition that affects the lung's tiniest airways, the bronchioles. In affected people, the bronchioles may become damaged and inflamed leading to extensive scarring that blocks the airways. Symptoms of the condition include a dry cough; shortness of breath; and/or fatigue and wheezing in the absence of a cold or asthma. Many different chemicals (such as nitrogen oxides, ammonia, welding fumes or food flavoring fumes) and respiratory infections can cause lung injury that leads to Bronchiolitis obliterans. It can also be associated with rheumatoid arthritis and graft-versus-host disease following a lung or hematopoietic cell transplantation. Another similarly named disease, Bronchiolitis obliterans organizing pneumonia, is a different disease.
What are the alternative names for Bronchiolitis Obliterans?
  • Bronchiolitis obliterans
  • Obliterative bronchiolitis
Who are the top Bronchiolitis Obliterans Local Doctors?
Dr. Hesham M. Elghannam
Pulmonary Medicine
Dr. Hesham M. Elghannam
Pulmonary Medicine

Aurora Medical Group, Inc.

2414 Kohler Memorial Dr, 
Sheboygan, WI 
 (2.5 mi)
920-457-4461
Languages Spoken:
English, Arabic
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Accepting New Patients
Offers Telehealth

Hesham Elghannam is a Pulmonary Medicine provider in Sheboygan, Wisconsin. Dr. Elghannam and is rated as an Experienced provider by MediFind in the treatment of Bronchiolitis Obliterans. His top areas of expertise are Obstructive Sleep Apnea, Excessive Daytime Sleepiness, Lung Nodules, Lung Metastases, and Advanced Bronchoscopy. Dr. Elghannam is currently accepting new patients.

Julie A. Biller
Dr. Julie A. Biller
Pulmonary Medicine | Pediatric Pulmonology
Dr. Julie A. Biller
Pulmonary Medicine | Pediatric Pulmonology

The Medical College Of Wisconsin Inc

Milwaukee, WI 
 (49.4 mi)
414-805-3666
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

Julie Biller is a Pulmonary Medicine specialist and a Pediatric Pulmonologist in Milwaukee, Wisconsin. Dr. Biller and is rated as an Advanced provider by MediFind in the treatment of Bronchiolitis Obliterans. Her top areas of expertise are Cystic Fibrosis, Secondary Immunodeficiency (SID), Newborn Jaundice, and Lung Metastases. Dr. Biller is currently accepting new patients.

 
 
 
 
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Dr. Jeffery R. Smale
Pulmonary Medicine | Intensive Care Medicine
Dr. Jeffery R. Smale
Pulmonary Medicine | Intensive Care Medicine

Froedtert Andthe Medical College Of Wisconsin Community Physicians Inc

3212 Pleasant Valley Rd, 
West Bend, WI 
 (33.8 mi)
262-334-6165
Languages Spoken:
English
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Accepting New Patients

Jeffery Smale is a Pulmonary Medicine specialist and an Intensive Care Medicine provider in West Bend, Wisconsin. Dr. Smale and is rated as an Experienced provider by MediFind in the treatment of Bronchiolitis Obliterans. His top areas of expertise are Lung Metastases, Chronic Obstructive Pulmonary Disease (COPD), Chronic Cough, Cerebral Hypoxia, and Gastrostomy. Dr. Smale is currently accepting new patients.

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What are the latest Bronchiolitis Obliterans Clinical Trials?
Nintedanib in Patients With Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem Cell Transplantation (HSCT)- a Multicentre Phase II Trial
Nintedanib in Patients With Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem Cell Transplantation (HSCT)- a Multicentre Phase II Trial
Who is this study for: Patients with Bronchiolitis Obliterans
Enrollment Status: Recruiting
Publish Date: February 19, 2025
Intervention Type: Drug
Study Drug: Nintedanib
Study Phase: Phase 2

Summary: This study investigates the safety and tolerability of Nintedanib in patients with bronchiolitis obliterans syndrome (BOS) following allogeneic hematopoietic cell transplantation. All study patients with BOS will be treated with the study drug Nintedanib (300 mg/day) as an add-on therapy to their basic immunosuppressive treatment over a 12-months treatment period.

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Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
Enrollment Status: Recruiting
Publish Date: February 18, 2025
Intervention Type: Device

Summary: This study is designed to measure the correlation of hyperpolarized 129-Xe magnetic resonance imaging (129-XeMRI) in allogeneic hematopoietic cell transplant (allo-HCT) recipients at MD Anderson Cancer Center (MDACC) who develop bronchiolitis obliterans syndrome (BOS) or BOS stage 0p (pulmonary impairment not meeting the definition for BOS, defined below) and controls with chronic graft-versus-hos...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center