High Flow Nasal Cannula Weaning in Acute Bronchiolitis - an Open-label Randomized Controlled Trials
Status: Recruiting
Location: See all (4) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this clinical study is to compared two different strategies to end high flow nasal cannula treatment in acute bronchiolitis. This study compared the immediate ending of high flow treatment to weaning strategy, in which the flow rate is gradually decreased. The aim is to assess if the immediate ending shortens the hospitalization time and whether it is a safe strategy.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 1
Healthy Volunteers: f
View:
• Clinically diagnosed acute bronchiolitis
• High flow nasal cannula treatment has lasted for at least 12 hours
• Measured saturation 95 or more with room air
• High flow rate is maximum 2l/kg/min
• The treating doctors considers the infant suitable to be without high flow
Locations
Other Locations
Finland
Siun Sote
RECRUITING
Joensuu
Central Finland Hospital District
RECRUITING
Jyväskylä
Kuopio University Hospital
RECRUITING
Kuopio
Mikkeli Central Hospital
RECRUITING
Mikkeli
Contact Information
Primary
Ilari Kuitunen, MD, PhD
ilari.kuitunen@uef.fi
+358447174910
Time Frame
Start Date: 2024-02-13
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 50
Treatments
Experimental: Immediate ending
High flow is ended immediately
Active_comparator: Weaning
High flow is ended by gradually reducing the flow rate
Related Therapeutic Areas
Sponsors
Collaborators: Siun sote, Central Finland Hospital District, Mikkeli Central Hospital
Leads: Kuopio University Hospital