Learn About Burkitt Lymphoma
Burkitt lymphoma (BL) is a very fast growing form of non-Hodgkin lymphoma.
B-cell lymphoma; High-grade B-cell lymphoma; Small noncleaved cell lymphoma; Burkitt's lymphoma
BL was first discovered in children in certain parts of Africa. It also occurs in the United States.
The African type of BL is closely associated with the Epstein-Barr virus (EBV), the main cause of infectious mononucleosis. The North American form of BL is not commonly linked to EBV.
People with HIV/AIDS have an increased risk for this condition. BL is most often seen in males.
BL may first be noticed as a swelling of the lymph nodes (glands) in the head and neck. These swollen lymph nodes are often painless, but can grow very rapidly.
In the types commonly seen in the United States, the cancer often starts in the belly area (abdomen). The disease can also start in the ovaries, testes, brain, kidneys, liver, and spinal fluid.
Other general symptoms may include:
- Fever
- Night sweats
- Unexplained weight loss
Chemotherapy is used to treat this type of cancer. If the cancer does not respond to chemotherapy alone, a bone marrow transplant may be done.
Bradhurst Avenue Specialty Office
Mitchell Cairo is a Hematologist and an Oncologist in Hawthorne, New York. Dr. Cairo is rated as an Elite provider by MediFind in the treatment of Burkitt Lymphoma. His top areas of expertise are Burkitt Lymphoma, B-Cell Lymphoma, Primary Mediastinal B-Cell Lymphoma (PMBCL), Non-Hodgkin Lymphoma, and Bone Marrow Transplant.
Jackson Orem practices in Kampala, Uganda. Mr. Orem is rated as an Elite expert by MediFind in the treatment of Burkitt Lymphoma. His top areas of expertise are Burkitt Lymphoma, Kaposi Sarcoma, B-Cell Lymphoma, Tissue Biopsy, and Gastrostomy.
Lorenz Trumper practices in Goettingen, Germany. Mr. Trumper is rated as an Elite expert by MediFind in the treatment of Burkitt Lymphoma. His top areas of expertise are Non-Hodgkin Lymphoma, Peripheral T-Cell Lymphoma, B-Cell Lymphoma, Burkitt Lymphoma, and Bone Marrow Transplant.
More than one half of people with BL can be cured with intensive chemotherapy. The cure rate may be lower if the cancer spreads to the bone marrow or spinal fluid. The outlook is poor if the cancer comes back after a remission or does not go into remission as a result of the first cycle of chemotherapy.
Possible complications of BL include:
- Complications of treatment
- Spread of the cancer
Contact your provider if you have symptoms of BL.
Summary: This phase II trial studies how well naive T-cell depletion works in preventing chronic graft-versus-host disease in children and young adults with blood cancers undergoing donor stem cell transplant. Sometimes the transplanted white blood cells from a donor attack the body's normal tissues (called graft versus host disease). Removing a particular type of T cell (naive T cells) from the donor cell...
Background: B-cell lymphoma is a cancer of white blood cells found in the lymph nodes. It affects the system that fights infections and disease. Researchers want to learn how certain drugs work together to treat B-cell lymphomas. The drugs are venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide (ViPOR).
Published Date: June 17, 2024
Published By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Abramson JS. Non-Hodgkin lymphomas. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 103.
Said JW. Immunodeficiency-related lymphoproliferative disorders. In: Hsi ED, ed. Hematopathology: Foundations of Diagnostic Pathology. 3rd ed. Philadelphia, PA: Elsevier; 2018:chap 10.
Schooley RT, Allen UD. Epstein-Barr virus infection. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 348.