Burkitt LymphomaSymptoms, Doctors, Treatments, Advances & More
Learn About Burkitt Lymphoma
Burkitt lymphoma (BL) is a very fast growing form of non-Hodgkin lymphoma.
B-cell lymphoma; High-grade B-cell lymphoma; Small noncleaved cell lymphoma; Burkitt's lymphoma
BL was first discovered in children in certain parts of Africa. It also occurs in the United States.
The African type of BL is closely associated with the Epstein-Barr virus (EBV), the main cause of infectious mononucleosis. The North American form of BL is not commonly linked to EBV.
People with HIV/AIDS have an increased risk for this condition. BL is most often seen in males.
BL may first be noticed as a swelling of the lymph nodes (glands) in the head and neck. These swollen lymph nodes are often painless, but can grow very rapidly.
In the types commonly seen in the United States, the cancer often starts in the belly area (abdomen). The disease can also start in the ovaries, testes, brain, kidneys, liver, and spinal fluid.
Other general symptoms may include:
- Fever
- Night sweats
- Unexplained weight loss
Chemotherapy is used to treat this type of cancer. If the cancer does not respond to chemotherapy alone, a bone marrow transplant may be done.
Emory Winship Cancer Institute
Kristie Blum is a Hematologist Oncology provider in Atlanta, Georgia. Dr. Blum has been practicing medicine for over 29 years and is rated as an Elite provider by MediFind in the treatment of Burkitt Lymphoma. Her top areas of expertise are Mantle Cell Lymphoma (MCL), Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Bone Marrow Transplant, and Bone Marrow Aspiration.
HMH - John Theurer Cancer Center - Hackensack
Tatyana Feldman is an Oncologist and a Hematologist in Hackensack, New Jersey. Dr. Feldman is rated as an Elite provider by MediFind in the treatment of Burkitt Lymphoma. Her top areas of expertise are Classical Hodgkin Lymphoma, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Bone Marrow Transplant, and Bone Marrow Aspiration.
Cardiology Consultants
Mitchell Cairo is a Pediatrics provider in Hawthorne, New York. Dr. Cairo is rated as an Elite provider by MediFind in the treatment of Burkitt Lymphoma. His top areas of expertise are Burkitt Lymphoma, B-Cell Lymphoma, Primary Mediastinal B-Cell Lymphoma (PMBCL), Non-Hodgkin Lymphoma, and Bone Marrow Transplant.
More than one half of people with BL can be cured with intensive chemotherapy. The cure rate may be lower if the cancer spreads to the bone marrow or spinal fluid. The outlook is poor if the cancer comes back after a remission or does not go into remission as a result of the first cycle of chemotherapy.
Possible complications of BL include:
- Complications of treatment
- Spread of the cancer
Contact your provider if you have symptoms of BL.
Summary: This is a Phase 1/2, first-in-human, open-label, dose-escalating trial designed to assess the safety and efficacy of VNX-101 in patients with relapsed or refractory CD19-positive hematologic malignancies.
Summary: This phase Ib/II trial tests the safety, side effects, best dose and how well giving CX-5461 works for the treatment of patients with B-cell non-Hodgkin lymphoma. CX-5461 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving CX-5461 may be safe, tolerable and/or effective in treating patients with B-cell non-Hodgkin lymphoma.
Published Date: June 17, 2024
Published By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Abramson JS. Non-Hodgkin lymphomas. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 103.
Said JW. Immunodeficiency-related lymphoproliferative disorders. In: Hsi ED, ed. Hematopathology: Foundations of Diagnostic Pathology. 3rd ed. Philadelphia, PA: Elsevier; 2018:chap 10.
Schooley RT, Allen UD. Epstein-Barr virus infection. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 348.