CACH Syndrome Clinical Trials

Find CACH Syndrome Clinical Trials Near You

A Randomized Controlled Trial of Music-4-MS Compared to Music Listening to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Multiple sclerosis (MS) rates in the U.S. have nearly doubled over the past decade, making it a leading cause of nontraumatic functional impairment in young adults and significantly affecting cognitive function in up to 70% of people with MS. While traditional cognitive rehabilitation methods are limited in sensory engagement, music training offers a multisensory approach that enhances neuroplasticity and improves cognitive functions. This study investigates the feasibility of Music-4-MS, a 12-week music-based eHealth intervention, to support cognitive and emotional health in individuals with MS.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Diagnosed with multiple sclerosis (relapsing remitting, secondary progressive, primary progressive)

• Diagnosed more than 6 months prior to starting study

• Self-reported cognitive impairment as assessed by having at leased 5 problems sometimes or more often on the Perceived Deficits Questionnaire

• Read, write, and understand English

• Access to internet

Locations
United States
Texas
University of Texas at Austin
RECRUITING
Austin
Contact Information
Primary
Carolyn Phillips, PhD, RN
carolyn.phillips@nursing.utexas.edu
512-475-7039
Time Frame
Start Date: 2026-08-10
Estimated Completion Date: 2028-08
Participants
Target number of participants: 64
Treatments
Experimental: Musical Training Intervention
Participants randomized to this arm receive a 12-week intervention to teach them how to play the ukulele. The ukulele is a very manageable instrument to learn and requires less hand dexterity than other stringed instruments. Each week participants will follow the musical training intervention (MTI) protocol that provides instruction on how to tune, hold, and strum the ukulele and play basic chords. To practice the chords, they will also learn popular songs (e.g., Chain of Fools, Three Little Birds, Happy Birthday, Just the Way You Are, and Coconut). Participants will be instructed to follow each session outlined weekly and asked to practice the instrument for at least 30 minutes, 5 days a week. They will be given a paper and digital version of the MTI protocol. A member of our research team will call the participants weekly to answer any questions about the MTI protocol.
Active_comparator: Music Listening
Participants randomized to this arm will be asked to listen to their preferred music for at least 30 minutes, 5 days a week. A member of our research team will call them every week to answer any questions they have about the ML protocol. They will be asked to record their experience in a daily log.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Nursing Research (NINR)
Leads: University of Texas at Austin

This content was sourced from clinicaltrials.gov