MediFind
Condition

Calciphylaxis

Condition 101

What is the definition of Calciphylaxis?

Calciphylaxis is a disease in which blood vessels (veins and arteries) become blocked by a build-up of calcium in the walls of the vessels, preventing blood from flowing to the skin or internal organs.  The lack of blood flow (ischemia) damages healthy tissue and causes it to die (necrosis).  The most obvious and frequent symptom of calciphylaxis is damage to the skin, as ulcers can develop and become infected easily.  Calciphylaxis can also affect fat tissue, internal organs, and skeletal muscle, causing infections, pain, and organ failure.  These symptoms are often irreversible, and many individuals with calciphylaxis may not survive more than a few months after they are diagnosed due to infection that spreads throughout the body (sepsis), or organ failure.  The exact cause of calciphylaxis is unknown.  Treatments may include medications to reduce pain, antibiotics to treat infections, and various approaches to preventing the development or worsening of this condition.bsp;to die (necrosis ...

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What are the alternative names for Calciphylaxis?

  • Idiopathic calciphylaxis

Latest Research

Latest Advance
Study
  • Condition: Tumoral Calcinosis (TC) in Uremic Patients with Secondary Hyperparathyroidism (SHPT)
  • Journal: BMC surgery
  • Treatment Used: Parathyroidectomy (PTX)
  • Number of Patients: 9
  • Published —
This study investigated the relationship between parathyroidectomy (PTX) and shrinkage of tumoral calcinosis (TC), a rare disease derived from uremic secondary hyperparathyroidism (SHPT).
Latest Advance
Study
  • Condition: Single Infected Calciphylaxis Lesion
  • Journal: Wounds : a compendium of clinical research and practice
  • Treatment Used: Intralesional Injection of Sodium Thiosulfate (STS) at High Concentration
  • Number of Patients: 1
  • Published —
This case report discusses a 51-year-old man with end-stage renal disease (ESRD) diagnosed with an infected calciphylaxis lesion and treated with intralesional injection of sodium thiosulfate (STS).

Clinical Trials

Clinical Trial
Other
  • Status: Recruiting
  • Participants: 300
  • Start Date: January 2017
Partners Calciphylaxis Biobank and Patient Registry
Clinical Trial
Other
  • Status: Recruiting
  • Participants: 1000
  • Start Date: December 2015
European Calciphylaxis Registry Network